Cardiovascular Disease

Heart Disease: Labs & Diagnostic Tests

This video clip is from episode #203 — AMA #34: What causes heart disease? — originally released on April 18,…

Mental & Emotional Health

Prioritizing “real friends” over “deal friends”

According to a May 2021 survey, Americans report having fewer close friendships than they did 30 years ago. But according to a recent conversation I had with author and social scientist Arthur Brooks, friendship is one of the key factors in finding and maintaining happiness as we age. 

 

Nutritional Biochemistry

Different effects of fat- vs. carbohydrate-restriction on neural reward signaling

“A calorie is a calorie” seems like a simple and obvious statement. But do different macronutrients vary in their ability to drive obesity? A recent study by Dr. Kevin Hall and colleagues provides new clues – and likely new fodder for debate.

Insulin Resistance

The five main tools for managing blood glucose numbers

This clip is from AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions, originally released on…

Medications, Supplements & Other Treatments

Vitamin D(éjà vu): new study, same old problems

For vitamin D supplementation to have any effect relative to placebo, it needs to be increasing the body’s supply of vitamin D, and if it doesn’t, then the treatment and placebo groups are effectively identical. So did the researchers achieve a difference in vitamin D levels over the course of the study?

Preventing Chronic Disease

First Case of Human PCSK9 Gene-Editing

Ultimately, the long-term benefits of lowering apoB through a one-time treatment may make this not only a viable future option, but potentially an intervention that could change preventive cardiovascular medicine.

Strength & Muscle Mass

Avoiding Injury Part II: Grip Strength

Not enough can be said about the importance of grip strength as you age. It’s one of the strongest physical associations with longer life.

Cognitive Health & Neurodegenerative Disease

Alzheimer’s disease — what labs can tell you about your risk

This clip is from AMA #14: What lab tests can (and cannot) inform us about our overall objective of longevity,…

Cognitive Health & Neurodegenerative Disease

Why does Alzheimer’s disease affect more women than men?

This clip is from episode #138 – Lauren Miller Rogen and Richard Isaacson, M.D.: Alzheimer’s disease prevention—patient and doctor perspectives,…

Stability

Avoiding Injury Part I: Eccentric Strength

Accidental injury is among the leading causes of death in the developed world, and even when an injury itself is not directly responsible for ending one’s life, the associated debilitation can hasten the onset and progression of other health concerns.

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