Medications, Supplements & Other Treatments

Taurine improves the health and longevity of mice and monkeys – but what about humans?

A new study set off a media storm over taurine’s potential in delaying aging and extending lifespan. Great news – if you’re a mouse.

Exercise & Physical Health

Cumulative time spent in “vigorous” physical activity lowers mortality risk

But the effects of frequent, sub-minute bouts of high-intensity movement have not convinced me to change my exercise routine.

Nutritional Biochemistry

Does carbohydrate load impact the balance between fat storage and oxidation?

A study investigated the effects of different dietary levels of carbohydrates on mitochondrial respiration, but mechanistic conclusions are premature.

Medications, Supplements & Other Treatments

Separating substance from nonsense in a study on NMN supplements

A recent randomized trial investigated the effect of NMN supplementation on NAD levels, biological aging, and exercise performance. What can we believe from their results?

Preventing Chronic Disease

“The cholesterol paradox”: a catchy phrase for an idea with no substance

A recent study reported that hypercholesterolemia is associated with reduced mortality, but it falls short of upsetting conventional wisdom

Medications, Supplements & Other Treatments

Clearing the air on hormone replacement therapy

My recent podcast with Dr. JoAnn Manson evidently raised as many questions about HRT as it answered, so let’s take a closer look at the evidence for risks and benefits.

Nutritional Biochemistry

Don’t drink and science: why a study on the cognitive effects of wine and cheese is sheer stupidity

A study claiming that daily consumption of cheese and wine may improve long-term cognition seems more like a bad joke than reliable science.

Exercise & Physical Health

Supramaximal exercise transiently raises serum uric acid

Why exercise-related acute fluctuations in this biomarker shouldn’t be a cause for distress

Medications, Supplements & Other Treatments

Is a recent clinical trial enough to support the use of semaglutide in treating adolescent obesity?

The imperative for effective weight management strategies in children and teens is clear, but in our desperation for effective obesity treatments, are we allowing ourselves to be too shortsighted on testing?

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