Patients often tell me they would like to live as long as they reasonably can, provided they do not suffer cognitive decline. More often than not, people care less about how long they live and more about how well they live, specifically as it pertains to their brain.
Anyone who has seen a relative suffer from a neurodegenerative disease – such as dementia or Alzheimer’s disease – can no doubt relate to the debilitating nature of these conditions. Unlike heart disease and cancer, which kill directly, the fatal impact of neurodegenerative diseases is often indirect. While much is still unknown, data suggest that there are indeed things that can be done to ward off one’s risk of developing a neurodegenerative disease.
Below is a collection of past articles and podcasts exploring such tactics. My hope is that this content can serve as helpful resources to dive deeper into this topic as well as support your ongoing longevity journey.
“The function of the mitochondria and mitochondrial health are the ultimate mitigator of neurodegenerative diseases…just by reducing the potential for reactive oxygen species related damage.” — Dom D’Agostino
“I would like to translate what we’ve learned about the role of autophagy in cancer and that involves developing small molecules to inhibit autophagy for cancer therapy.” — Eileen White
Mendelian randomization and lifetime cardiovascular disease risk.
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If that weren’t enough to set me off, consider the overall weakness of this study, and the choice of the word “proven” borders on journalistic manslaughter.
Comments are welcomed and encouraged. The purpose of comments on our site is to expand knowledge, engage in thoughtful discussion, and learn more from readers.
Criticism and skepticism can be far more useful than praise and unflinching belief.
There’s an art and science to critical thinking and how to conduct yourself. There’s a multitude of fallacious appeals we could spell out, but a good rule of thumb is not to attack the person, attack the ideas. Don’t look for the flaws in the person, look for the flaws in the hypothesis. Let’s keep the brawling to movies depicting minor league hockey teams and political “news” shows.
Thank you for adding to the discussion.
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