Category

Cognitive Health & Neurodegenerative Disease

Patients often tell me they would like to live as long as they reasonably can, provided they do not suffer cognitive decline. More often than not, people care less about how long they live and more about how well they live, specifically as it pertains to their brain.

Anyone who has seen a relative suffer from a neurodegenerative disease – such as dementia or Alzheimer’s disease – can no doubt relate to the debilitating nature of these conditions. Unlike heart disease and cancer, which kill directly, the fatal impact of neurodegenerative diseases is often indirect. While much is still unknown, data suggest that there are indeed things that can be done to ward off one’s risk of developing a neurodegenerative disease.

Below is a collection of past articles and podcasts exploring such tactics. My hope is that this content can serve as helpful resources to dive deeper into this topic as well as support your ongoing longevity journey.

Mental & Emotional Health

Robin Williams

This Tuesday marks the tragic anniversary of the death of Robin Williams.

Ketosis

#120 – AMA with Dom D’Agostino, Ph.D., Part II of II: Ketosis for cancer and chronic disease, hyperbaric oxygen therapy, and the effect of ketosis on female health

“The function of the mitochondria and mitochondrial health are the ultimate mitigator of neurodegenerative diseases…just by reducing the potential for reactive oxygen species related damage.” — Dom D’Agostino

Ketosis

#116 – AMA with Dom D’Agostino, Ph.D., Part I of II: Ketogenic diet, exogenous ketones, and exercise

“If you restore insulin sensitivity, you’re better able to access and burn fat.” — Dom D’Agostino

Fasting

#114 – Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies

“I would like to translate what we’ve learned about the role of autophagy in cancer and that involves developing small molecules to inhibit autophagy for cancer therapy.” — Eileen White

Cognitive Health & Neurodegenerative Disease

Alzheimer’s disease and glucose metabolism

“In Alzheimer’s Research, Glucose Metabolism Moves to Center Stage.”

Diseases

LDL-C & systolic blood pressure and lifetime risk of cardiovascular disease

Mendelian randomization and lifetime cardiovascular disease risk.

Treatments

Qualy #46 – Rapamycin’s effects on cancer, cardiovascular disease, and neurodegeneration

Today’s episode of The Qualys is from podcast #09 – David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR…

Diseases

Qualy #24 – What are the “ABCs” of Alzheimer’s prevention?

Today’s episode of The Qualys is from podcast #18 – Richard Isaacson, M.D.: Alzheimer’s prevention.

Mental & Emotional Health

Qualy #16 – How much does cognitive activity ward off cognitive decline?

Today’s episode of The Qualys is from podcast #18 – Richard Isaacson, M.D.: Alzheimer’s prevention.

Understanding science

What can you prove?

If that weren’t enough to set me off, consider the overall weakness of this study, and the choice of the word “proven” borders on journalistic manslaughter.

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