Weekly Emails

Whether you drive an automatic or manual, here’s a game of driving that I like to play in order to stay hypervigilant, and I encourage you to play it: Imagine that someone on the road is trying to kill you today.

I had an obsession with cracking my knuckles. How the heck does it produce such a cool sound (people around me beg to differ on the degree of coolness)?

The deeper I get into exploring longevity, the more I feel compelled to understand death from reasons not related to the chronic diseases of aging.

“The great majority of how we understand disease, and attempt to cure it,” writes Engber, “derives from a couple of rodents.” About 4/5ths of all animal studies reported in biomedical research papers from 1950-2010 were done in rodents (59% in mice, 18% in rats).

Groundhog Day (GD) came and went last month — and sure enough — 2019 has already brought a bounty of emails and Tweets from concerned folks wondering if red meat is going to kill them (again).

For someone—me—who has a tumultuous relationship with his inbox, recommending a daily email should give you some idea of how highly I regard these.

I read an interesting article authored by my friend Dom D’Agostino and his colleagues on the anti-catabolic effects of ketone bodies in skeletal muscle.

This article shares some compelling evidence, in mice at least, showing how information about the paternal environment reaches the womb.

So much to explore with this one. Mental health may be the hardest chapter for me to write in my book, and also the most important.

Perhaps a bigger takeaway from this article is the approach this particular group takes: a consortium from different fields converging on the problem is likely the right way to address a problem as daunting as Alzheimer’s disease.