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#279 – AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins
“It is worth noting, and this is a very important question, that it does not appear that the effect of statins on insulin resistance is a function of lipids being lowered.” —Peter Attia
#277 ‒ Food allergies: causes, prevention, and treatment with immunotherapy | Kari Nadeau, M.D., Ph.D.
“What I love about the immune system is it can be trained, and you just need to know how to train it.” —Kari Nadeau
Is the frequency of menopausal symptoms an early barometer for later-in-life brain health?
More than “bothersome”: Frequent menopausal hot flashes during sleep are associated with greater white matter hyperintensity volume
Is testosterone replacement therapy both safe and effective in men with higher cardiovascular risk factors?
An assessment of the results from the long-awaited TRAVERSE trial
#276 ‒ Special episode: Peter answers questions on longevity, supplements, protein, fasting, apoB, statins, and more
“One of the most important things to understand when you are using some sort of intervention is, do you have a biomarker to know if you’re doing it correctly?” —Peter Attia
#274 – Performance-enhancing drugs and hormones: risks, rewards, and broader implications for the public | Derek: More Plates, More Dates
“There’s no drug that’s purely selective exactly where you want and it’s perfect.” —Derek – More Plates More Dates
Therapeutic potential and cardiovascular risks of medical cannabis
A recent study highlights concerns regarding the potential cardiovascular risks associated with using medical cannabis. A cause for alarm?
#271 – AMA #51: Understanding and improving your metabolic health
“Zone 2 output is arguably the most important functional test we have of metabolic health.” —Peter Attia
#268 ‒ Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D.
“There are literally tens of thousands of genetic variants in your genome, and what they mean and whether or not they do anything whatsoever is hard to know.” —Wendy Chung
#262 – AMA #49: Heart rate recovery, strength training, rucking, kidney function, and brain health
“[Heart rate recovery] is one of the metrics that we should care about just as we care about VO2 max and just as we care about resting heart rate.” —Peter Attia