Learn more about Peter Attia’s digital program
Is the frequency of menopausal symptoms an early barometer for later-in-life brain health?
More than “bothersome”: Frequent menopausal hot flashes during sleep are associated with greater white matter hyperintensity volume
#276 ‒ Special episode: Peter answers questions on longevity, supplements, protein, fasting, apoB, statins, and more
“One of the most important things to understand when you are using some sort of intervention is, do you have a biomarker to know if you’re doing it correctly?” —Peter Attia
#271 – AMA #51: Understanding and improving your metabolic health
“Zone 2 output is arguably the most important functional test we have of metabolic health.” —Peter Attia
Can treating hearing loss improve cognitive trajectories and reduce dementia risk?
Age-related hearing loss is very common and has long been known to correlate strongly with cognitive decline. A just-published randomized trial sought to evaluate causality in this association. What do we know now?
#257 ‒ Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies, supplements, and more | Tommy Wood, M.D., Ph.D.
“If you’re trying to maintain a basic set of cognitive functions, [it is important] to actively work on ways to increase headroom, increase absolute capacity throughout the lifespan. Because at some point capacity will decrease, but you want to push that out as far as you can.” —Tommy Wood
#252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting | Rhonda Patrick, Ph.D.
“My perspective has shifted as any scientist that’s following data should… When new data comes out, you have to reassess things.” —Rhonda Patrick
#251 – AMA #46: Optimizing brain health: Alzheimer’s disease risk factors, APOE, prevention strategies, and more
“The bottom line here is the earlier you were diagnosed with type 2 diabetes, the higher your risk of dementia.” —Peter Attia
A recent metformin study casts doubts on longevity indications
A new retrospective study contradicts previous evidence of metformin’s potential effects on lifespan extension in a general population, but for real answers, randomized trials are needed.
#240 ‒ The confusion around HDL and its link to cardiovascular disease | Dan Rader, M.D.
“HDL cholesterol itself is not directly and causally protective against atherosclerotic cardiovascular disease.” —Dan Rader
#236 ‒ Neurodegenerative disease: pathology, screening, and prevention | Kellyann Niotis, M.D.
“When you think of brain health, it’s not just the cognitive piece, but it’s the movement piece too.” ‒ Kellyann Niotis