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#246 – AMA #45: Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent
“The thing that concerns me the most with these drugs. . .is this drive towards sarcopenia.” —Peter Attia
#238 – AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease
“ApoB is a necessary, though not sufficient, factor in the development of ASCVD which means the more you lower it, the more you lower risk. Full stop.” —Peter Attia
#211 – AMA #36: Fruits & vegetables—everything you need to know
“There’s also a very significant cultural and social component to this thing as well. So I think that’s where the tribalism comes from around nutrition.” —Peter Attia
#204 – Centenarians, metformin, and longevity | Nir Barzilai, M.D.
“If you prevent aging and age-related disease, you’re going to compress morbidity, too.” — Nir Barzilai
Can a father’s metformin cause birth defects in his sons?
Several studies have examined the effects of both maternal diabetes and maternal metformin exposure on offspring, but prospective fathers have received comparatively little attention. A recent study sought to change that.
How deadly is type 2 diabetes?
Diabetes was only the 8th-leading cause of death in 2020. Can it really be possible that diabetes is so “harmless” relative to the other major chronic diseases, or are the CDC reports only the tip of the iceberg?
#201 – Deep dive back into Zone 2 | Iñigo San-Millán, Ph.D. (Pt. 2)
“You can accomplish very important mitochondrial adaptations and very important metabolic adaptations by exercising one hour.” —Iñigo San-Millán
Peter Attia on the role of exercise in mitigating and reversing insulin resistance
This clip is from “Ask Me Anything” (AMA) episode #20, originally released on February 15, 2021. If you’re a member, you…
Peter Attia on How Insulin Resistance Manifests in the Muscle
“If you’re in the business of wanting to live the healthiest life you can live, which means longer and better, you’ve got to be insulin sensitive, full stop.” — Peter Attia
#184 – AMA #29: GLP-1 Agonists – The Future of Treating Obesity?
“Getting deeper into how this drug works has certainly made me appreciate its power.” —Peter Attia