Tag

Drugs – metformin

Exercise

#85 – Iñigo San Millán, Ph.D.: Mitochondria, exercise, and metabolic health

“What I have been seeing for 25 years, working with elite athletes, is that [zone 2] is the exercise intensity where I see the biggest improvement in fat burning and the biggest improvement in lactic clearance capacity. Therefore, that means that the mitochondria is where you see the biggest improvement.” —Iñigo  San Millán, Ph.D.

Treatments

Metformin and exercise – déjà vu all over again?

Metformin blunts muscle hypertrophy in response to progressive resistance training

Exercise

#73 – AMA #9: NAD & metformin, fat-burning zone, creatine, estrogenization of men, emergency kit for cold & flu, and more

“The sky is blue, and the trees are green; therefore, I should eat cyanide.” — Peter Attia on the type of brilliant logic people use to suggest you burn more calories while sleeping vs. exercising

Aging

Did a recent study show we can reverse aging?

I dig a little deeper into the recent study that suggests (to some) the answer is yes.

Aging

Can you reverse your biological age?

I realize it may seem like Groundhog Day for you to see more prose from me about how to think about studies rather than the tactical bits we think we can immediately extract and employ from them. Just remember, it’s better to learn how to fish than to be given … you get it.

Aging

#67 – AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more

“If you are genetically blessed to become a centenarian, the gift you got is that you have genes that delay your receipt of chronic disease by what appears to be about 20 years.” — Peter Attia

Aging

#66 – Vamsi Mootha, M.D.: Aging, type 2 diabetes, cancer, Alzheimer’s disease, and Parkinson’s disease – do all roads lead to mitochondria?

“We have 300 different forms of monogenic mitochondrial diseases. . .and these are terrible diseases and we need therapies for them. . .but it’s also our hope that studying some of them will provide insights into the common form of aging as well.” —Vamsi Mootha

Treatments

Metformin and exercise

If you like concrete answers and absolutes, longevity is not a fun sandbox to play in.

Sleep

#45 – AMA #4: sleep, jet lag protocol, autophagy, metformin, and more

“Every day in the human body, some 10 billion cells die and are replaced by new cells.” —Nick Lane

Aging

#35 – Nir Barzilai, M.D.: How to tame aging

“I think the prevention of aging is really a good place to be. . .and I think life is going to be very different in the next decade with our advances.” —Nir Barzilai

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