Tag

Drugs – metformin

#207 – AMA #35: “Anti-Aging” Drugs — NAD+, metformin, & rapamycin

“It’s really hard to know, in my view, how important sirtuins are as longevity factors…If we accept that, then it’s difficult to know [the importance of] activation of sirtuins by NAD as a longevity mechanism.” —Matt Kaeberlein

About TAME: A Metformin Anti-Aging Clinical Trial with Nir Barzilai, M.D.

This video clip is from episode #204 – Centenarians, metformin, and longevity with Nir Barzilai, M.D., originally released on April…

#204 – Centenarians, metformin, and longevity | Nir Barzilai, M.D.

If you prevent aging and age-related disease, you’re going to compress morbidity, too.” — Nir Barzilai

Can a father’s metformin cause birth defects in his sons?

Several studies have examined the effects of both maternal diabetes and maternal metformin exposure on offspring, but prospective fathers have received comparatively little attention. A recent study sought to change that.

#201 – Deep dive back into Zone 2 | Iñigo San-Millán, Ph.D. (Pt. 2)

You can accomplish very important mitochondrial adaptations and very important metabolic adaptations by exercising one hour.” —Iñigo San-Millán

Qualys #241 – The genetic gift of centenarians

This episode of The Qualys is from podcast #35, Nir Barzilai, M.D.: How to tame aging, which was originally released on January 7, 2019.

#184 – AMA #29: GLP-1 Agonists – The Future of Treating Obesity?

“Getting deeper into how this drug works has certainly made me appreciate its power.” —Peter Attia

#175 – Matt Kaeberlein, Ph.D.: The biology of aging, rapamycin, and other interventions that target the aging process

“I don’t think I will ever understand aging fully. And I don’t think the field will. … But I also believe that we don’t have to understand it fully to be able to have an impact on the biology of aging through interventions.” —Matt Kaeberlein

#171 – Steve Austad, Ph.D.: The landscape of longevity science: making sense of caloric restriction, biomarkers of aging, and possible geroprotective molecules

“I never thought [extending the human lifespan] was going to happen because we got better at treating cancer or we got better at preventing heart disease. I always thought it was going to happen because we would develop something … that would fundamentally change the rate of aging. And we haven’t developed that yet. We’ve got a lot of clues and I think we’re getting closer and closer and closer.” —Steve Austad

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