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#204 – Centenarians, metformin, and longevity | Nir Barzilai, M.D.
“If you prevent aging and age-related disease, you’re going to compress morbidity, too.” — Nir Barzilai
Can a father’s metformin cause birth defects in his sons?
Several studies have examined the effects of both maternal diabetes and maternal metformin exposure on offspring, but prospective fathers have received comparatively little attention. A recent study sought to change that.
#201 – Deep dive back into Zone 2 | Iñigo San-Millán, Ph.D. (Pt. 2)
“You can accomplish very important mitochondrial adaptations and very important metabolic adaptations by exercising one hour.” —Iñigo San-Millán
Qualys #241 – The genetic gift of centenarians
This episode of The Qualys is from podcast #35, Nir Barzilai, M.D.: How to tame aging, which was originally released on January 7, 2019.
#184 – AMA #29: GLP-1 Agonists – The Future of Treating Obesity?
“Getting deeper into how this drug works has certainly made me appreciate its power.” —Peter Attia
#175 – Matt Kaeberlein, Ph.D.: The biology of aging, rapamycin, and other interventions that target the aging process
“I don’t think I will ever understand aging fully. And I don’t think the field will. … But I also believe that we don’t have to understand it fully to be able to have an impact on the biology of aging through interventions.” —Matt Kaeberlein
#171 – Steve Austad, Ph.D.: The landscape of longevity science: making sense of caloric restriction, biomarkers of aging, and possible geroprotective molecules
“I never thought [extending the human lifespan] was going to happen because we got better at treating cancer or we got better at preventing heart disease. I always thought it was going to happen because we would develop something … that would fundamentally change the rate of aging. And we haven’t developed that yet. We’ve got a lot of clues and I think we’re getting closer and closer and closer.” —Steve Austad
Metformin and COVID-19 mortality risk; a timeline of Kobe’s last day
A few things worth checking out: 03-28-2021
#148 – Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the Interventions Testing Program
“I don’t really care what causes aging. What I care about is: What is the process that can postpone all the different aspects of aging?” — Rich Miller
#140 – Gerald Shulman, M.D., Ph.D.: A masterclass on insulin resistance—molecular mechanisms and clinical implications
“If we can understand insulin resistance, then that’s going to be the best way to fix diabetes, heart disease,. . .fatty liver disease, and slow down cancers.” — Gerald Shulman