Tag

Drugs – PCSK9i

#279 – AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins

It is worth noting, and this is a very important question, that it does not appear that the effect of statins on insulin resistance is a function of lipids being lowered.” —Peter Attia

#276 ‒ Special episode: Peter answers questions on longevity, supplements, protein, fasting, apoB, statins, and more

One of the most important things to understand when you are using some sort of intervention is, do you have a biomarker to know if you’re doing it correctly?” —Peter Attia

#238 – AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease

ApoB is a necessary, though not sufficient, factor in the development of ASCVD which means the more you lower it, the more you lower risk. Full stop.” —Peter Attia

#231 – AMA #41: Medicine 3.0, developments in the field of aging, healthy habits in times of stress, and more

“We have reached the limits of medicine 2.0 capacity, and if longevity is something we are aspiring for, we need a new strategy.” —Peter Attia

#230 ‒ Cardiovascular disease in women: prevention, risk factors, lipids, and more | Erin Michos, M.D.

How we live the first half of our lives really influences our freedom for morbidity and mortality the second half of our lives.” —Erin Michos

PCSK9 inhibitors

The genetics of PCSK9i nonresponders

A recent case study shines light on why some individuals are resistant to PCSK9 inhibitors. 

Peter’s approach to managing patients with high Lp(a)

This video is a clip from episode #210 – Lp(a) and its impact on heart disease with Benoît Arsenault, Ph.D.,…

#210 – Lp(a) and its impact on heart disease | Benoît Arsenault, Ph.D.

I think we should advise people to measure Lp(a); that would be a gigantic step.” —Benoît Arsenault

Low LDL cholesterol and neural development

Why LDL-lowering treatments don’t pit head against heart

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