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#80 – Celebrity AMA with Apolo Ohno and Sasha Cohen: Fasting, rapamycin, performance vs. longevity, and more
“I am obsessed with knowing stuff. There’s just no denying it.” — Peter Attia
Qualy #46 – Rapamycin’s effects on cancer, cardiovascular disease, and neurodegeneration
Today’s episode of The Qualys is from podcast #09 – David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR…
#59 – Jason Fung, M.D.: Fasting as a potent antidote to obesity, insulin resistance, type 2 diabetes, and the many symptoms of metabolic illness
“We think of all these responses, obesity, insulin resistance, and the beta cell failure, as pathologic. They’re actually protective. . .Your body is actually trying to protect itself against the root cause of the problem which is too much insulin, too much glucose.” — Jason Fung
#37 – Zubin Damania, M.D.: Revolutionizing healthcare one hilariously inspiring video at a time
“The idea that you can optimize a particular regiment to the goals of that unique patient is the foundation of what we call Health 3.0.” —Zubin Damania
#10 – Matt Kaeberlein, Ph.D.: rapamycin and dogs — man’s best friends? — living longer, healthier lives and turning back the clock on aging and age-related diseases
“I believe that rigorously demonstrating that we can increase healthspan and lifespan in pet dogs will be a huge step toward gaining the support and credibility that the field needs.” —Matt Kaeberlein
#09 – David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR — the nexus of aging and longevity?
“It’s the happenstance of science that makes it interesting.” —David Sabatini
Robin Williams, Globalism on the brink, rapamycin and lifespan
I think seeing a picture of Robin this week on Lance Armstrong’s Instagram page got me thinking about him. I still remember exactly where I was the moment I found out about his death.
Studying Studies: Part V – power and significance
Studies can be statistically powerful and significant, but practically weak and meaningless (and vice versa).
Back to the future
The most interesting paper I (re-)read this week was “Twenty-five years of mTOR: Uncovering the link from nutrients to growth,” by my buddy David Sabatini.