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Targeting senescent cells for cognitive health
With the recent publication of the first clinical trial of senolytics for AD treatment, popular interest in these drugs has swelled, but is the excitement justified?
The difference between a ‘clean’ drug and a ‘dirty’ drug
This clip is from episode #207 – AMA #35: “Anti-Aging” Drugs — NAD+, metformin, & rapamycin, originally released on May…
#207 – AMA #35: “Anti-Aging” Drugs — NAD+, metformin, & rapamycin
“It’s really hard to know, in my view, how important sirtuins are as longevity factors…If we accept that, then it’s difficult to know [the importance of] activation of sirtuins by NAD as a longevity mechanism.” —Matt Kaeberlein