#290 ‒ Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the future of aging research | Alex Aravanis, M.D., Ph.D.
“Age is your single biggest risk factor for cancer. The population over 50 is about a 10x increased risk relative to the population under 50.” —Alex Aravanis
“Biological” clocks: a peek into the future or a haphazard guess of mortality?
Potential uses for the epigenetics of aging and why I don’t put much stock in epigenetics-based aging clocks at present
#222 ‒ How nutrition impacts longevity | Matt Kaeberlein, Ph.D.
“It’s really important that we be willing to change our beliefs about nutrition and other aspects of health as more data comes in.” —Matt Kaeberlein
#207 – AMA #35: “Anti-Aging” Drugs — NAD+, metformin, & rapamycin
“It’s really hard to know, in my view, how important sirtuins are as longevity factors…If we accept that, then it’s difficult to know [the importance of] activation of sirtuins by NAD as a longevity mechanism.” —Matt Kaeberlein
#204 – Centenarians, metformin, and longevity | Nir Barzilai, M.D.
“If you prevent aging and age-related disease, you’re going to compress morbidity, too.” — Nir Barzilai