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Epigenetics – epigenetic clocks

#290 ‒ Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the future of aging research | Alex Aravanis, M.D., Ph.D.

Age is your single biggest risk factor for cancer. The population over 50 is about a 10x increased risk relative to the population under 50.” —Alex Aravanis

“Biological” clocks: a peek into the future or a haphazard guess of mortality?

Potential uses for the epigenetics of aging and why I don’t put much stock in epigenetics-based aging clocks at present

#222 ‒ How nutrition impacts longevity | Matt Kaeberlein, Ph.D.

It’s really important that we be willing to change our beliefs about nutrition and other aspects of health as more data comes in.” —Matt Kaeberlein

#207 – AMA #35: “Anti-Aging” Drugs — NAD+, metformin, & rapamycin

“It’s really hard to know, in my view, how important sirtuins are as longevity factors…If we accept that, then it’s difficult to know [the importance of] activation of sirtuins by NAD as a longevity mechanism.” —Matt Kaeberlein

The challenges of defining aging with Matt Kaeberlein, Ph.D.

This video clip is from episode #175 – The biology of aging, rapamycin, and other interventions that target the aging…

#204 – Centenarians, metformin, and longevity | Nir Barzilai, M.D.

If you prevent aging and age-related disease, you’re going to compress morbidity, too.” — Nir Barzilai

#175 – Matt Kaeberlein, Ph.D.: The biology of aging, rapamycin, and other interventions that target the aging process

“I don’t think I will ever understand aging fully. And I don’t think the field will. … But I also believe that we don’t have to understand it fully to be able to have an impact on the biology of aging through interventions.” —Matt Kaeberlein

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