#116 – AMA with Dom D’Agostino, Ph.D., Part I of II: Ketogenic diet, exogenous ketones, and exercise
“If you restore insulin sensitivity, you’re better able to access and burn fat.” — Dom D’Agostino
#114 – Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies
“I would like to translate what we’ve learned about the role of autophagy in cancer and that involves developing small molecules to inhibit autophagy for cancer therapy.” — Eileen White
#108 – AMA #13: 3-day fasting, exogenous ketones, autophagy, and exercise for longevity
“I think once people enter that seventh and eighth decade, if they haven’t done a lot of consistent preparatory work in the decades prior, it’s alarming how quickly things go south.” —Peter Attia
#92 – AMA #12: Strategies for longevity (which don’t require a doctor)
“If you are interested in longevity, if you are interested in playing with your great grandkids, you want to prioritize muscle mass. Never in the history of civilization has a 90 year old said, ‘I wish I had less muscle.’” —Peter Attia
#89 – AMA #11: All things fasting
“Truthfully, in humans, we don’t necessarily know exactly what the dose curve looks like for duration of fasting to physiologic output of desired consequence.” —Peter Attia
#88 – Paul Grewal, M.D.: Treating metabolic disease and strategies for long-term health
“You could say our food supply has changed more in the last 100 years than it has in the last 10,000.” — Paul Grewal
A new year
A couple of unrelated events over the past few months have led me to view 2020 as a year to implement some new routines around my mental and emotional health.
#85 – Iñigo San Millán, Ph.D.: Mitochondria, exercise, and metabolic health
“What I have been seeing for 25 years, working with elite athletes, is that [zone 2] is the exercise intensity where I see the biggest improvement in fat burning and the biggest improvement in lactic clearance capacity. Therefore, that means that the mitochondria is where you see the biggest improvement.” —Iñigo San Millán, Ph.D.
#84 – AMA #10: Low testosterone, hypothyroidism, building muscle (and preserving it while fasting)
“Milk is for babies. When you grow up you have to drink beer.” —Arnold Schwarzenegger
#80 – Celebrity AMA with Apolo Ohno and Sasha Cohen: Fasting, rapamycin, performance vs. longevity, and more
“I am obsessed with knowing stuff. There’s just no denying it.” — Peter Attia