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“DNA diets” are still a long way off from offering an easier route to weight loss
A recent study reports that leveraging genetics to inform diet choice is ineffective in promoting weight loss beyond the effects of calorie restriction alone
#290 ‒ Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the future of aging research | Alex Aravanis, M.D., Ph.D.
“Age is your single biggest risk factor for cancer. The population over 50 is about a 10x increased risk relative to the population under 50.” —Alex Aravanis
#268 ‒ Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D.
“There are literally tens of thousands of genetic variants in your genome, and what they mean and whether or not they do anything whatsoever is hard to know.” —Wendy Chung
Twenty Years of the Human Genome: Growing Older and Wiser
In the 20 years since the Human Genome Project was completed in 2003, we’ve dramatically expanded our understanding of the impact of genetics on human health, but the work is far from finished.
#213 ‒ Liquid biopsies and cancer detection | Max Diehn, M.D. Ph.D.
“I was frustrated by not being able to diagnose a recurrence earlier.” —Max Diehn
#70 – David Sinclair, Ph.D.: How cellular reprogramming could slow our aging clock (and the latest research on NAD)
In this episode, David Sinclair, Ph.D., a Professor in the Department of Genetics at Harvard Medical School and co-Director of…
#66 – Vamsi Mootha, M.D.: Aging, type 2 diabetes, cancer, Alzheimer’s disease, and Parkinson’s disease – do all roads lead to mitochondria?
“We have 300 different forms of monogenic mitochondrial diseases. . .and these are terrible diseases and we need therapies for them. . .but it’s also our hope that studying some of them will provide insights into the common form of aging as well.” —Vamsi Mootha
#51 – Robert Sapolsky, Ph.D.: The pervasive effect of stress – is it killing you?
“The [stress response] system has been serving vertebrates, doing a lot of help for them for an awful long time, and it’s only been a very recent modification to instead secrete [cortisol] in response to thinking about taxes.” —Robert Sapolsky