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#281 ‒ Longevity drugs, aging biomarkers, and updated findings from the Interventions Testing Program (ITP) | Rich Miller, M.D., Ph.D.
“What we try to do is quite simple. We try to find drugs that will slow aging and extend mouse lifespan.” —Rich Miller
Could an antihypertensive drug have independent benefits for longevity?
A recent animal study indicates that the antihypertensive drug rilmenidine has impressive effects on lifespan, but without further evidence, this story seems like another “fountain of youth” myth.
Are there “biomarkers” for aging?
This clip is from “Ask Me Anything” (AMA) episode #35, originally released on May 16, 2022. If you’re a member,…
#207 – AMA #35: “Anti-Aging” Drugs — NAD+, metformin, & rapamycin
“It’s really hard to know, in my view, how important sirtuins are as longevity factors…If we accept that, then it’s difficult to know [the importance of] activation of sirtuins by NAD as a longevity mechanism.” —Matt Kaeberlein
About TAME: A Metformin Anti-Aging Clinical Trial with Nir Barzilai, M.D.
This video clip is from episode #204 – Centenarians, metformin, and longevity with Nir Barzilai, M.D., originally released on April…
Lessons from centenarians: why prevention of chronic disease is critical
“To me, the takeaway for us, as physicians or people who want to have an extra five years of life or 10 years of life… is nothing matters more than prevention of chronic disease. And by the way, you don’t get to prevent it once you have your heart attack. Secondary prevention is not prevention.” – Peter Attia, M.D.
#204 – Centenarians, metformin, and longevity | Nir Barzilai, M.D.
“If you prevent aging and age-related disease, you’re going to compress morbidity, too.” — Nir Barzilai
How useful are home DNA kits?
This video clip is from AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more, originally released…
#67 – AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more
“If you are genetically blessed to become a centenarian, the gift you got is that you have genes that delay your receipt of chronic disease by what appears to be about 20 years.” — Peter Attia