Tag

Hormones – insulin

Nutritional biochemistry

Cortisol and cross-pollination

Cortisol is a hormone I’ve been paying a lot more attention to of late.

Fasting

Fast-breaking without glucose spiking

As I’m coming off of a week of fasting and heading into a week of a ketogenic diet, the timing seems right to address the question of how I break a longer-term fast and the responses that some people get.

Fasting

#59 – Jason Fung, M.D.: Fasting as a potent antidote to obesity, insulin resistance, type 2 diabetes, and the many symptoms of metabolic illness

“We think of all these responses, obesity, insulin resistance, and the beta cell failure, as pathologic. They’re actually protective.  . .Your body is actually trying to protect itself against the root cause of the problem which is too much insulin, too much glucose.” — Jason Fung

Treatments

Metformin and exercise

If you like concrete answers and absolutes, longevity is not a fun sandbox to play in.

Diseases

#41 – Jake Kushner, M.D.: How to thrive with type 1 diabetes and how everyone can benefit from the valuable insights

“You have this unique population of [type 1 diabetics] where you can see the insulin that goes into them, and you can see it’s direct impact on weight gain. . . and they’re at risk for cardiovascular illness. And to me that just says that there’s something about the Standard American Diet that’s making us sick. And ultimately we will all be at risk for cardiovascular disease.” —Jake Kushner

Diseases

#30 – Thomas Seyfried, Ph.D.: Controversial discussion—cancer as a mitochondrial metabolic disease?

“The standard of care should never have been written in granite. It should be flexible. If you have something else that comes along that might be better, you’d think there would be enthusiasm.” —Tom Seyfried

Aging

#09 – David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR — the nexus of aging and longevity?

“It’s the happenstance of science that makes it interesting.” —David Sabatini

Diseases

Is Type 2 Diabetes Reversible at Scale?

If you’re reading this, you probably know that I’m obsessed with longevity.

Nutritional biochemistry

How to make a fat cell less not thin: the lessons of fat flux

Does being in ketosis automatically translate to fat loss?

Nutritional biochemistry

Is sugar toxic?

I remember one of my mentors in surgical residency made a very important distinction for me.  He said, “Peter, never forget what you are getting paid to do, and what you are doing for free.”  You see, there are some aspects of being a surgeon that are not particularly enjoyable.  The hours are long.  Sometimes…

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