#204 – Centenarians, metformin, and longevity | Nir Barzilai, M.D.
“If you prevent aging and age-related disease, you’re going to compress morbidity, too.” — Nir Barzilai
Peter Attia on the connection between stress and insulin resistance
This clip is from “Ask Me Anything” (AMA) episode #17, originally released on November 9, 2020. If you’re a member, you…
#194 – How fructose drives metabolic disease | Rick Johnson, M.D.
“Fructose turns out to have been meant to be this wonderful system for survival, but in our culture with the amount of sugar in foods that we are eating (that either provide sugar or can be turned into fructose), this pathway has become hazardous.” —Rick Johnson
#184 – AMA #29: GLP-1 Agonists – The Future of Treating Obesity?
“Getting deeper into how this drug works has certainly made me appreciate its power.” —Peter Attia
#180 – AMA #28: All things testosterone and testosterone replacement therapy
“There were countless other studies to look at, but they all basically point in the same direction, which is testosterone replacement therapy improves lean mass, reduces fat mass, improves strength.” —Peter Attia
#173 – AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions
“Zone two is a metabolic state. It’s not determined by speed. It’s determined by which energy system you’re requiring and what the equilibrium is.” —Peter Attia
#163 – Layne Norton, Ph.D.: Building muscle, losing fat, and the importance of resistance training
“I always tell people, I don’t think I would’ve had the success I did in business or social media or academia if I hadn’t done weightlifting because that taught me so much about other things in life.” —Layne Norton
#141 – AMA #18: Deep dive: sugar and sugar substitutes
“Is glucose a sugar? Yes. Is fructose a sugar? Yes. Are they the same? Not even close.” —Peter Attia
#136 – AMA #17: Body composition methods tour de force, insulin resistance, and Topo Chico
“Skeletal muscles are the greatest reservoir that you have for glucose disposal.” —Peter Attia
#124 – AMA #15: Real-world case studies—metabolic dysregulation, low testosterone, menopause, and more
As a follow up to AMA #14 where Peter explained his framework for analyzing labs, this “Ask Me Anything” (AMA)…