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#279 – AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins
“It is worth noting, and this is a very important question, that it does not appear that the effect of statins on insulin resistance is a function of lipids being lowered.” —Peter Attia
The five main tools for managing blood glucose numbers
This clip is from AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions, originally released on…
The difference between maximum aerobic capacity and efficiency
This video clip is from #151 – Alex Hutchinson, Ph.D.: Translating the science of endurance and extreme human performance, originally…
Breaking down VO2 max: Definition, history, why it plateaus, and whether it really matters
This video clip is from #151 – Alex Hutchinson, Ph.D.: Translating the science of endurance and extreme human performance, originally…
Can a father’s metformin cause birth defects in his sons?
Several studies have examined the effects of both maternal diabetes and maternal metformin exposure on offspring, but prospective fathers have received comparatively little attention. A recent study sought to change that.
How deadly is type 2 diabetes?
Diabetes was only the 8th-leading cause of death in 2020. Can it really be possible that diabetes is so “harmless” relative to the other major chronic diseases, or are the CDC reports only the tip of the iceberg?
Why is maintaining weight loss more challenging than losing weight?
This video clip is taken from Podcast #197 — The science of obesity & how to improve nutritional epidemiology with David…
#197 – The science of obesity & how to improve nutritional epidemiology | David Allison, Ph.D.
“How much does obesity kill you because it stigmatizes you and it creates some stress?” —David Allison
#173 – AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions
“Zone two is a metabolic state. It’s not determined by speed. It’s determined by which energy system you’re requiring and what the equilibrium is.” —Peter Attia
#161 – AMA #23: All Things Nicotine: deep dive into its cognitive and physical benefits, risks, and mechanisms of action
“It’s so fascinating to me frankly that one molecule found in nature can be so potent. It’s hard to imagine you could engineer a drug to do this.” —Peter Attia