Tag

Metabolism – NAD

Aging

#175 – Matt Kaeberlein, Ph.D.: The biology of aging, rapamycin, and other interventions that target the aging process

“I don’t think I will ever understand aging fully. And I don’t think the field will. … But I also believe that we don’t have to understand it fully to be able to have an impact on the biology of aging through interventions.” —Matt Kaeberlein

Treatments

Does NMN improve metabolic health in humans?

Thoughts on the first efficacy trial recently published

Treatments

#148 – Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the Interventions Testing Program

“I don’t really care what causes aging. What I care about is: What is the process that can postpone all the different aspects of aging?” — Rich Miller

Aging

Qualy #57 – A primer on NAD+/NADH, its effect on lifespan/healthspan, and a review of the supplements

Today’s episode of The Qualys is from podcast #02 – Rhonda Patrick, Ph.D.: the performance and longevity paradox of IGF-1,…

Exercise

#73 – AMA #9: NAD & metformin, fat-burning zone, creatine, estrogenization of men, emergency kit for cold & flu, and more

“The sky is blue, and the trees are green; therefore, I should eat cyanide.” — Peter Attia on the type of brilliant logic people use to suggest you burn more calories while sleeping vs. exercising

Aging

#70 – David Sinclair, Ph.D.: How cellular reprogramming could slow our aging clock (and the latest research on NAD)

In this episode, David Sinclair, Ph.D., a Professor in the Department of Genetics at Harvard Medical School and co-Director of…

Aging

#66 – Vamsi Mootha, M.D.: Aging, type 2 diabetes, cancer, Alzheimer’s disease, and Parkinson’s disease – do all roads lead to mitochondria?

“We have 300 different forms of monogenic mitochondrial diseases. . .and these are terrible diseases and we need therapies for them. . .but it’s also our hope that studying some of them will provide insights into the common form of aging as well.” —Vamsi Mootha

Nutritional biochemistry

#46 – Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease – NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine and more

“People are gonna make a decision to. . . either wait 10 or 20 years until we know something better, or you take the position that you’re going to tinker. And if you’re going to tinker, you’re a lot more successful if you have a working model of what’s going on than if you don’t.” —Chris Masterjohn

Aging

#35 – Nir Barzilai, M.D.: How to tame aging

“I think the prevention of aging is really a good place to be. . .and I think life is going to be very different in the next decade with our advances.” —Nir Barzilai

Nutritional biochemistry

#31 – Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease

“I pay more attention today to stress than anything else.” —Nav Chandel

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