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Understanding science

Understanding science

#143 – John Ioannidis, M.D., D.Sc.: Why most biomedical research is flawed, and how to improve it

“We need to defend our method. We need to defend our principles. We need to defend the honesty of science in trying to communicate it rather than building exaggerated promises or narratives that are not realistic.” —John Ioannidis

COVID-19

A few things worth checking out: 12-13-2020

COVID-19 vaccine concerns; visualizing cell signaling pathways; IQ points

Understanding science

Randomized controlled trials: when the gold standard leaves you with fool’s gold

If I told you that I read a randomized double-blinded placebo-controlled trial conducted over 5 years and carried out in over 18,000 participants, is there any scenario under which you would not believe it to be an excellent trial?

Understanding science

The importance of red teams

“The first principle is that you must not fool yourself—and you are the easiest person to fool.” —Richard Feynman

Mental models

#96 – David Epstein: How a range of experience leads to better performance in a highly specialized world

“Sometimes the things you can do to cause the most rapid appearance of short-term progress can undermine long-term development.” — David Epstein

Nutritional biochemistry

The red meat and plant-based recommendation wars

Does reducing meat consumption improve health?

Understanding science

Nobel retractions

On January 2nd, Arnold made headlines after announcing she and her co-authors retracted a paper that was published in the prestigious journal Science in May of 2019, 7 months after winning the Nobel Prize.

Fasting

Intermittent fasting

Metabolic switching and different forms of fasting.

Understanding science

Qualy #65 – The three laws of medicine — Law #1: A strong intuition is much more powerful than a weak test

Today’s episode of The Qualys is from podcast #32 – Siddhartha Mukherjee, M.D., Ph.D.: new frontiers in cancer therapy, medicine,…

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