#180 – AMA #28: All things testosterone and testosterone replacement therapy
“There were countless other studies to look at, but they all basically point in the same direction, which is testosterone replacement therapy improves lean mass, reduces fat mass, improves strength.” —Peter Attia
#173 – AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions
“Zone two is a metabolic state. It’s not determined by speed. It’s determined by which energy system you’re requiring and what the equilibrium is.” —Peter Attia
Are continuous glucose monitors a waste of time for people without diabetes?
Some experts suggest CGMs are useless for nondiabetics. I disagree.
#165 – AMA #24: Deep dive into blood glucose: why it matters, important metrics to track, and superior insights from a CGM
“Hyperinsulinemia on an [oral glucose tolerance test], even in the presence of normoglycemia, is the canary in the coal mine.” —Peter Attia
#148 – Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the Interventions Testing Program
“I don’t really care what causes aging. What I care about is: What is the process that can postpone all the different aspects of aging?” — Rich Miller
#141 – AMA #18: Deep dive: sugar and sugar substitutes
“Is glucose a sugar? Yes. Is fructose a sugar? Yes. Are they the same? Not even close.” —Peter Attia
#110 – Lew Cantley, Ph.D.: Cancer metabolism, cancer therapies, and the discovery of PI3K
“If I get a result that suddenly doesn’t make sense, to me that’s more exciting. . .if you figure out why it didn’t work and what was wrong, then that’s where most breakthroughs come from.” — Lew Cantley
Alzheimer’s disease and glucose metabolism
“In Alzheimer’s Research, Glucose Metabolism Moves to Center Stage.”
#89 – AMA #11: All things fasting
“Truthfully, in humans, we don’t necessarily know exactly what the dose curve looks like for duration of fasting to physiologic output of desired consequence.” —Peter Attia
#87 – Rick Johnson, M.D.: Metabolic Effects of Fructose
“Fructose turns out to be used by animals as a mechanism to store fat.” — Rick Johnson