#173 – AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions
“Zone two is a metabolic state. It’s not determined by speed. It’s determined by which energy system you’re requiring and what the equilibrium is.” —Peter Attia
Are continuous glucose monitors a waste of time for people without diabetes?
Some experts suggest CGMs are useless for nondiabetics. I disagree.
#165 – AMA #24: Deep dive into blood glucose: why it matters, important metrics to track, and superior insights from a CGM
“Hyperinsulinemia on an [oral glucose tolerance test], even in the presence of normoglycemia, is the canary in the coal mine.” —Peter Attia
#148 – Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the Interventions Testing Program
“I don’t really care what causes aging. What I care about is: What is the process that can postpone all the different aspects of aging?” — Rich Miller
#141 – AMA #18: Deep dive: sugar and sugar substitutes
“Is glucose a sugar? Yes. Is fructose a sugar? Yes. Are they the same? Not even close.” —Peter Attia
#110 – Lew Cantley, Ph.D.: Cancer metabolism, cancer therapies, and the discovery of PI3K
“If I get a result that suddenly doesn’t make sense, to me that’s more exciting. . .if you figure out why it didn’t work and what was wrong, then that’s where most breakthroughs come from.” — Lew Cantley
Alzheimer’s disease and glucose metabolism
“In Alzheimer’s Research, Glucose Metabolism Moves to Center Stage.”
#89 – AMA #11: All things fasting
“Truthfully, in humans, we don’t necessarily know exactly what the dose curve looks like for duration of fasting to physiologic output of desired consequence.” —Peter Attia
#87 – Rick Johnson, M.D.: Fructose—The common link in high blood pressure, insulin resistance, T2D, & obesity?
“Fructose turns out to be used by animals as a mechanism to store fat.” — Rick Johnson
#69 – Ronesh Sinha, M.D.: Insights into the manifestation of metabolic disease in a patient population predisposed to metabolic syndrome, and what it teaches us more broadly
“The way we raise our kids early on might actually set a pattern for how much of an accelerated life, or how much of a stressed out nervous system they might have later on. . . a lot of the behavioral patterns that we’re instilling in our kids are kind of setting the foundation for insulin resistance and inflammation early on.” —Ronesh Sinha