Is a recent clinical trial enough to support the use of semaglutide in treating adolescent obesity?
The imperative for effective weight management strategies in children and teens is clear, but in our desperation for effective obesity treatments, are we allowing ourselves to be too shortsighted on testing?
To reduce appetite, skip late-night snacks
Two recent randomized trials found that biasing food intake toward the end of the day increases appetite and may reduce energy expenditure.
#227 – AMA #40: Body composition, protein, time-restricted feeding, fasting, DEXA scans, and more
“We don’t want to be consuming protein for energy purposes at all. We want to be consuming protein for muscle protein synthesis.” —Peter Attia
Different effects of fat- vs. carbohydrate-restriction on neural reward signaling
“A calorie is a calorie” seems like a simple and obvious statement. But do different macronutrients vary in their ability to drive obesity? A recent study by Dr. Kevin Hall and colleagues provides new clues – and likely new fodder for debate.
#212 – The neuroscience of obesity | Stephan Guyenet, Ph.D.
“This system works better at protecting against fat loss than it does against fat gain.” —Stephan Guyenet
#205 – Energy balance, nutrition, & building muscle | Layne Norton, Ph.D. (Pt.2)
“Lean body mass is inversely proportional to your risk of mortality after age 50.” —Layne Norton
Should BMI be used? Measuring obesity at the individual level
This video clip is taken from Podcast #197 — The science of obesity & how to improve nutritional epidemiology with David…