#18 – Richard Isaacson, M.D.: Alzheimer’s prevention
“Anyone with a brain is at risk for Alzheimer’s.” —Richard Isaacson
High-intensity interval training and cognitive function in older adults: promising but limited findings
A new study indicates that HIIT may help delay or even reverse age-related declines in memory and learning, but this exercise modality remains just one aspect of a well-balanced regimen.
#313 – AMA #62: Protein’s impact on appetite and weight management, and uric acid’s link to disease and how to manage levels
“The body responds in pretty significant ways to alterations in protein availability.” —Peter Attia
#311 ‒ Longevity 101: a foundational guide to Peter’s frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more
“I would say three-quarters of the benefits you can get towards a longer life, come solely from pursuing better health.” —Peter Attia
Don’t underestimate the importance of oral health
A meta-analysis reports that toothbrushing reduced the risk of hospital-acquired pneumonia among ICU patients, hinting at the whole-body impacts of oral hygiene
Does hormone replacement therapy impact dementia risk?
A recent case-control study reports that menopausal hormone therapy is associated with increased risk of dementia, but results have little relevance for modern clinical practice
#306 – AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more
“Metabolic health, first and foremost, is the goal of nutrition.” —Peter Attia
Is Alzheimer’s disease unavoidable for individuals with a high-risk APOE genotype?
A recent study reporting nearly 100% penetrance of the high-risk APOE-e4 variant is a lesson on the importance of unbiased sampling
#303 – A breakthrough in Alzheimer’s disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer’s disease | Dena Dubal, M.D., Ph.D.
“I have this dream that people might be able someday to benefit from klotho, this factor that naturally circulates in our body, that helps with longevity, that helps with other organ systems and enhances the brain.” —Dena Dubal
#300 – Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise?
“The probability that having a high VO2 max, high muscle mass, and high muscle strength are going to increase the length of your life and improve the quality of your life. . .is so high that to act in disregard of that is irresponsible.” —Peter Attia
Aerobic exercise for Parkinson’s disease
The neuroprotective nature of aerobic exercise influences a variety of Parkinson’s disease symptoms, on top of its role in impacting disease risk and progression