QPS
Peter’s key takeaways on bone health, calorie restriction, gene editing and more
#325 ‒ Peter’s key takeaways on bone health, calorie restriction and energy balance, dopamine and addiction, gene editing, and testosterone therapy safety with a prostate cancer diagnosis | Quarterly Podcast Summary #3
In this quarterly podcast summary (QPS) episode, Peter summarizes his biggest takeaways from the last three months of guest interviews on the podcast. Peter shares key insights from his discussions on diverse topics such as dopamine and addiction with Anna Lembke, the current state and exciting future of CRISPR-mediated gene editing with Feng Zhang, how to build and maintain strong bones from youth to old age with Belinda Beck, how calorie restriction may influence longevity and metabolic health with Eric Ravussin, and the role of testosterone and TRT in prostate cancer with Ted Schaeffer. Additionally, Peter shares any personal behavioral adjustments or modifications to his patient care practices that have arisen from these engaging discussions.
- Overview of topics to be covered [1:45];
- Anna Lembke episode: addiction, dopamine’s role in pleasure and pain, and managing addictive behaviors [4:15];
- Follow-up questions about addiction: heritability, cold therapy, exercise, and strategies for breaking addictive behaviors [14:45];
- Feng Zhang episode: the potential of gene editing with CRISPR technology for treating diseases and the challenges ahead [21:00];
- Feng Zhang’s impactful education experience, and how early exposure and curiosity-driven learning can develop scientific interest for kids [28:30];
- The future of CRISPR: weighing the scientific potential to combat complex diseases against ethical considerations around genetic modification [33:45];
- Belinda Beck episode: how to build and maintain strong bones from youth to old age [37:30];
- How both nutrition and exercise are crucial for bone health at all ages, and why it’s never too late to start [54:45];
- Eric Ravussin episode: calorie restriction, energy expenditure, exercise for weight maintenance, and more [59:00];
- Measuring energy intake and energy expenditure: techniques and challenges [1:09:45];
- Ted Schaeffer episode: the nuance role of testosterone in prostate cancer, TRT, and the need for better cancer biomarkers [1:14:30];
- Peter’s favorite bands [1:25:45]; and
- More.
QPS
Peter's key takeaways on liver health, heart rate variability, AI in medicine, klotho, and lactate metabolism
#319 ‒ Peter’s key takeaways on liver health, heart rate variability, AI in medicine, klotho, and lactate metabolism | Quarterly Podcast Summary #2
In this quarterly podcast summary (QPS) episode, Peter summarizes his biggest takeaways from the last three months of guest interviews on the podcast. Peter shares key insights from each episode, covering diverse topics such as liver health with Julia Wattacheril, heart rate variability with Joel Jamieson, artificial intelligence with Zak Kohane, klotho for brain health with Dena Dubal, and lactate and lactate metabolism with George Brooks. Additionally, Peter shares any personal behavioral adjustments or modifications to his patient care practices that have arisen from these engaging discussions.
- Overview of topics, and the positive feedback on the quarterly podcast summary format [2:00];
- Julia Wattacheril episode: liver health and disease [4:00];
- Noninvasive methods to diagnose liver conditions, and how to manage and improve liver health [16:00];
- Joel Jamieson episode: heart rate variability (HRV) for training and health [27:15];
- Practical tools for measuring HRV and how it informs training and recovery decisions [37:00];
- Zak Kohane episode: artificial intelligence and medicine [47:15];
- The current role of AI in medicine and how it could revolutionize medicine in the future [53:45];
- The limitations and concerns pertaining to AI [1:00:15];
- Dena Dubal episode: the potential benefits of klotho for brain health [1:05:00];
- Animal studies on klotho and brain health [1:11:00];
- Genetics-based variations in klotho levels in humans and their impact on cognition, disease risk, and longevity [1:14:15];
- Testing klotho levels, the significance of the KL-VS variant, the role of exercise in increasing klotho, and more [1:17:30];
- The potential of klotho as a treatment for cognitive decline and Alzheimer’s disease [1:23:15];
- George Brooks episode: a new paradigm to think about lactate and lactate metabolism [1:27:45];
- The potential for lactate infusions to aid in brain recovery following a head injury [1:34:00];
- The relationship between lactate and cancer, and the impact of exercise on lactate levels and cancer risk [1:36:30]; and
- More.
