The Peter Attia Drive Podcast

The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. Topics include fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more.

The Drive is hosted by Dr. Peter Attia, a Stanford/Johns Hopkins/NIH-trained physician focusing on the applied science of longevity, the extension of human life and well-being.

Featured Podcasts

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#01 – Tim Ferriss: depression, psychedelics, and emotional resilience

“It’s very hard for people to talk their way out of something that they didn’t talk their way into.” —Tim Ferriss

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#47 – Matthew Walker, Ph.D., on sleep – Part I of III: Dangers of poor sleep, Alzheimer’s risk, mental health, memory consolidation, and more

“I think that sleep may be one of the most significant lifestyle factors that determines your risk ratio for Alzheimer’s disease.” — Matthew Walker

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#59 – Jason Fung, M.D.: Fasting as a potent antidote to obesity, insulin resistance, type 2 diabetes, and the many symptoms of metabolic illness

“We think of all these responses, obesity, insulin resistance, and the beta cell failure, as pathologic. They’re actually protective.  . .Your body is actually trying to protect itself against the root cause of the problem which is too much insulin, too much glucose.” — Jason Fung

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#34 – Sam Harris, Ph.D.: The transformative power of mindfulness

“Thought really is the obstacle one is overcoming when learning to meditate.” —Sam Harris

“ ” I've always been fascinated with medicine. I really enjoy his take on things, his clarity, the brilliant guests he has on, and how out of my depth it all is. Jason Fried
Jason FriedCo-Founder & CEO, Basecamp
“ ” Your podcasts are like a massive gift to humanity. I've been enjoying them very much. Michael Dell
Michael DellFounder and CEO, Dell Technologies

Recent Podcasts

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#74 – Jason Fried: Optimizing efficiency and work-life balance

“People brag about how little sleep they get, and how much they work. I don’t understand that…if you really ask them about why they’re working so long, it’s not that there’s more work to do, it’s that there’s less time to do good work, because people’s days are broken into smaller and smaller and smaller chunks of time…And before you know it’s the end of the day and you’ve got nothing done even though you’ve been busy all day.” —Jason Fried

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#73 – AMA #9: NAD & metformin, fat-burning zone, creatine, estrogenization of men, emergency kit for cold & flu, and more

“The sky is blue, and the trees are green; therefore, I should eat cyanide.” — Peter Attia on the type of brilliant logic people use to suggest you burn more calories while sleeping vs. exercising

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#72 – Dan Harris: 10% happier – meditation, kindness, and compassion

“Mindfulness is the ability to know what’s happening in your head at any given moment without getting carried away by it.” — Dan Harris

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#71 – Katherine Eban: Widespread fraud in the generic drug industry

“Generics are supposed to be this great leveler. It’s like the democratization of drugs that the rich and the poor alike can have access to for these great cures. To find out…that the companies cashing in on that image are really selling that short in a very devious way, is painful to realize. It’s a real great public health hope that has a very dark underbelly.” — Katherine Eban

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#70 – David Sinclair, Ph.D.: How cellular reprogramming could slow our aging clock (and the latest research on NAD)

In this episode, David Sinclair, Ph.D., a Professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging, returns to the podcast to discuss the content of his new book, Lifespan: Why We Age – and Why We Don’t Have To. This…

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#69 – Ronesh Sinha, M.D.: Insights into the manifestation of metabolic disease in a patient population predisposed to metabolic syndrome, and what it teaches us more broadly

“The way we raise our kids early on might actually set a pattern for how much of an accelerated life, or how much of a stressed out nervous system they might have later on. . . a lot of the behavioral patterns that we’re instilling in our kids are kind of setting the foundation for insulin resistance and inflammation early on.” —Ronesh Sinha

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#68 – Marty Makary, M.D.: The US healthcare system—why it’s broken, steps to fix it, and how to protect yourself

“We’re trying to empower people in the United States to say we need a competent and fair pricing system.” — Marty Makary

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#67 – AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more

“If you are genetically blessed to become a centenarian, the gift you got is that you have genes that delay your receipt of chronic disease by what appears to be about 20 years.” — Peter Attia

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#66 – Vamsi Mootha, M.D.: Aging, type 2 diabetes, cancer, Alzheimer’s disease, and Parkinson’s disease – do all roads lead to mitochondria?

“We have 300 different forms of monogenic mitochondrial diseases. . .and these are terrible diseases and we need therapies for them. . .but it’s also our hope that studying some of them will provide insights into the common form of aging as well.” —Vamsi Mootha

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#65 – Rick Doblin, Ph.D.: MDMA — the creation, scheduling, toxicity, therapeutic use, and changing public opinion of what is possibly the single most important synthetic molecule ever created by our species

“I think that there’s a fundamental human right that people have to explore their consciousness. . .I believe we should have a system of licensed legalization [for psychedelics].” — Rick Doblin

Want to view all past podcasts on a single page? View our podcast archive.

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