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Peptides—evaluating the science, safety, and hype in a rapidly growing field

Ep. #387 (AMA #83)
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Updated cardiovascular guidelines—statin use in patients as young as 30

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Protect the eyes, protect the brain—a potentially simple lever for dementia risk

Ask Me Anything (AMA)

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Applying the tools of longevity in the real world: disease prevention, DEXA scans, artificial sweeteners, injury recovery, stability training, habit formation, protein intake and mTOR activation, and more

Ep. #385 (AMA #82)
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Special episode — Obicetrapib: The CETP inhibitor with cardiovascular benefits and potential Alzheimer's prevention

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An intriguing case of “exceptional resilience” against dementia

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Biological aging tests, longevity training, emerging therapies, GLP-1 RAs, sun exposure, and more

Ep. #383 (AMA #81)
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Longevity optimization through strength benchmarks, VO₂ max targets, nutrition principles, brain health, supplements, GLP-1 RAs, wearables, and more

Ep. #382 (AMA #80)
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Does lowering cholesterol harm the brain?

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GLP-1 Drugs Fail to Slow Cognitive Decline in Alzheimer’s Disease

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Navigating the complex relationship between statins, GLP-1, and glycemic control

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The absence of atherosclerosis is not an excuse to ignore heart attack symptoms—especially for women

Nutrition

Guest Episode

The seed oil debate: are they uniquely harmful relative to other dietary fats?

Ep. #380 with Layne Norton, Ph.D.
Risks

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Pitting facts against sensationalism regarding the role of LDL cholesterol in ASCVD

Exercise

Guest Episode

Women’s health and performance: how training, nutrition, and hormones interact across life stages

Ep. #378 with Abbie Smith-Ryan, Ph.D.
Longevity

AMA

Longevity interventions, exercise, diagnostic screening, and managing high apoB, hypertension, metabolic health, and more

Ep. #376 (AMA #78)
Risks

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Hope for millions: the selfless work of the “world’s most important doctor”

Nutrition

Guest Episode

The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer’s disease, brain injuries, and more

Ep. #375 with Dominic D’Agostino, Ph.D.
Medications & supplements

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Cardiovascular benefits of GLP-1 drugs independent of weight loss

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Thyroid function and hypothyroidism: why current diagnosis and treatment fall short for many, and how new approaches are transforming care

Ep. #373 with Antonio Bianco, M.D., Ph.D.
Longevity

AMA

Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — promising, proven, fuzzy, noise, or nonsense?

Ep. #370 (AMA #76)