Risks

One of the foundational lessons we can take away from studying centenarians — those who have lived to the age of 100+ — is that if you want to live longer, you have to live longer without chronic disease, not live longer with chronic disease. Unfortunately, our current healthcare system is primarily geared toward helping you live longer once you develop chronic disease. This, of course, is the opposite of the approach I take with my patients.

Over 80% of deaths in people over 50 who do not smoke can be grouped into 4 main categories, what I like to call the four horsemen of chronic disease. These are: (1) atherosclerotic disease (comprised of cardiovascular disease and cerebrovascular disease), (2) cancer, (3) neurodegenerative disease (Alzheimer’s disease being the most common), and (4) metabolic disease (a spectrum of everything from hyperinsulinemia to insulin resistance to fatty liver disease to type 2 diabetes).

We have five main longevity tactics at our disposal to affect our longevity: (1) exercise, (2) sleep, (3) nutrition, (4) medications & supplements, and (5) distress tolerance. Below is a collection of podcasts and articles discussing how we can use these tactics to mitigate, prevent, and reverse chronic disease.

Medications & supplements

Guest Episode

Women’s sexual health, menopause, and hormone replacement therapy (HRT)

Ep. #348 with Rachel Rubin, M.D.

Risks

Free Article

Do fat cells “remember” obesity even after weight loss?

Other tactics, tools, & treatments

QPS

Peter’s takeaways on mastering sleep, dealing with chronic pain, developing breakthrough cancer drugs, transforming healthcare with AI, advancing radiation therapy, and healing trauma

Ep. #347

Other tactics, tools, & treatments

Guest Episode

Scaling biotech and improving global health: lessons from an extraordinary career in medicine

Ep. #346 with Susan Desmond-Hellmann, M.D., M.P.H.

Longevity

Guest Episode

Chronic pain: pathways, treatment, and the path to physical and psychological recovery

Ep. #345 with Sean Mackey, M.D., Ph.D.

Risks

Free Article

Erectile dysfunction as an indicator of cardiovascular health

Other tactics, tools, & treatments

Guest Episode

The evolving role of radiation: advancements in cancer treatment, emerging low-dose treatments for arthritis, tendonitis, and injuries, and addressing misconceptions

Ep. #343 with Sanjay Mehta, M.D.

Longevity

Podcast Episode

Aging well: Peter shares strategies for improving longevity with residents at a senior living center

Ep. #342

Risks

Free Article

My personal home edits for reducing microplastic exposure

Sleep

Free Article

A reminder on the importance of sleep for brain health

Risks

Free Article

A causal link between obesity and autoimmune disease

Longevity

QPS

Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4

Ep. #338

Risks

Free Article

Concerning links between human papillomavirus (HPV) infection and male infertility

Risks

Podcast Episode

Insulin resistance masterclass: The full body impact of metabolic dysfunction and prevention, diagnosis, and treatment

Ep. #337 with Ralph DeFronzo, M.D.

Longevity

AMA

Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more

Ep. #336 (AMA #68)

Risks

Free Article

Compounding effects of multiple metabolic conditions on cardiovascular risk

Risks

Guest Episode

Cardiovascular disease, the number one killer: development, biomarkers, apoB, cholesterol, brain health, and more

Ep. #334 with Tom Dayspring, M.D.

Risks

AMA

Microplastics, PFAS, and phthalates: understanding health risks and a framework for minimizing exposure and mitigating risk

Ep. #332 (AMA #67)

Risks

Premium Article

All things blood pressure: from measurement to management

Risks

Free Article

Precautions against increased fall risk associated with antihypertensive drugs

Understanding science

Free Article

Research Worth Sharing, December 2024 Edition

Longevity

AMA

Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more

Ep. #329

Mental & Emotional Health

Free Article

When caution becomes concerning: the relationship between health anxiety and mortality

Nutrition

Free Article

Oldies-But-Goodies, December 2024 Edition