Cardiovascular Disease

One of the scariest things about heart disease is that it is often a silent killer, with few to no outward symptoms. As one of my medical school professors liked to point out, the most common “presentation” of the disease is a sudden, fatal heart attack. You know the patient has heart disease because he has just died from it.

And while mortality rates from those first, surprise heart attacks have dropped significantly thanks to improvements in basic cardiac life support and time-sensitive interventions, such attacks are still fatal roughly 1/3 of the time.

Below is a collection of past articles and podcasts related to heart disease prevention, atherosclerosis, coronary disease, cholesterol, apoB, and more.

Understanding science

Podcast Episode

How curiosity transforms medicine: extraordinary discoveries that changed modern healthcare

Ep. #401

Risks

AMA

Environmental pollution and longevity: air pollution, noise, light, EMFs, and practical strategies to mitigate health risks

Ep. #400 (AMA #87)

Risks

Free Article

The trouble with “good cholesterol”

Risks

Guest Episode

Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health

Ep. #395 with Tom Dayspring, M.D.

Risks

Free Article

The beginning of the end of atherosclerosis?

Risks

Podcast Episode

Genetic testing: when it's valuable, how to choose the right test, and what to do with the results

Ep. #392

Risks

AMA

Family health history, preventing heart disease, metabolic health, strength training efficiency, dementia risk reduction, NAD supplements, and hydration

Ep. #390 (AMA #84)

Risks

Premium Article

Reducing cardiovascular risk: a playbook for lipid-lowering pharmacotherapy

Medications & supplements

AMA

Peptides—evaluating the science, safety, and hype in a rapidly growing field

Ep. #387 (AMA #83)

Medications & supplements

Free Article

Updated cardiovascular guidelines—statin use in patients as young as 30

Ask Me Anything (AMA)

AMA

Applying the tools of longevity in the real world: disease prevention, DEXA scans, artificial sweeteners, injury recovery, stability training, habit formation, protein intake and mTOR activation, and more

Ep. #385 (AMA #82)

Risks

Podcast Episode

Special episode — Obicetrapib: The CETP inhibitor with cardiovascular benefits and potential Alzheimer's prevention

Ep. #384

Longevity

AMA

Biological aging tests, longevity training, emerging therapies, GLP-1 RAs, sun exposure, and more

Ep. #383 (AMA #81)

Medications & supplements

Premium Article

Navigating the complex relationship between statins, GLP-1, and glycemic control

Risks

Free Article

The absence of atherosclerosis is not an excuse to ignore heart attack symptoms—especially for women

Nutrition

Guest Episode

The seed oil debate: are they uniquely harmful relative to other dietary fats?

Ep. #380 with Layne Norton, Ph.D.

Risks

Free Article

Pitting facts against sensationalism regarding the role of LDL cholesterol in ASCVD

Exercise

Guest Episode

Women’s health and performance: how training, nutrition, and hormones interact across life stages

Ep. #378 with Abbie Smith-Ryan, Ph.D.

Longevity

AMA

Longevity interventions, exercise, diagnostic screening, and managing high apoB, hypertension, metabolic health, and more

Ep. #376 (AMA #78)

Medications & supplements

Free Article

Cardiovascular benefits of GLP-1 drugs independent of weight loss

Longevity

AMA

Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — promising, proven, fuzzy, noise, or nonsense?

Ep. #370 (AMA #76)

Nutrition

Guest Episode

Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use

Ep. #369 with Rhonda Patrick, Ph.D.

Risks

Free Article

Artificially sweetened beverages for metabolic health: motivation matters

Risks

Free Article

When zero doesn’t mean zero: the limits of coronary calcium in women