Exercise

Podcast Episode

Building strength and muscle mass: how to optimize training, nutrition, and more for longevity (AMA #71 rebroadcast)

Medications & supplements

Free Article

Metformin and cancer: active surveillance needed

Medications & supplements

AMA

GLP-1 RAs and muscle loss: new data, better questions, and how to preserve muscle during weight loss

Ep. #398 (AMA #86)
Risks

Guest Episode

Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health

Ep. #395 with Tom Dayspring, M.D.
Sleep

Podcast Episode

Sleep pharmacology: the role of medications in healthy sleep, the promise of emerging therapies, and the evidence for common sleep supplements

Ep. #394
Medications & supplements

Premium Article

Growth hormone for musculoskeletal system repair

Medications & supplements

AMA

#393 ‒ AMA #85: A guide to medications and supplements: determining what to take, what to skip, and how to know if they’re working for you

Risks

AMA

Family health history, preventing heart disease, metabolic health, strength training efficiency, dementia risk reduction, NAD supplements, and hydration

Ep. #390 (AMA #84)
Medications & supplements

Free Article

Disappointing results from the first rapamycin-plus-exercise trial

Medications & supplements

AMA

Peptides—evaluating the science, safety, and hype in a rapidly growing field

Ep. #387 (AMA #83)
Medications & supplements

Free Article

Updated cardiovascular guidelines—statin use in patients as young as 30

Ask Me Anything (AMA)

AMA

Applying the tools of longevity in the real world: disease prevention, DEXA scans, artificial sweeteners, injury recovery, stability training, habit formation, protein intake and mTOR activation, and more

Ep. #385 (AMA #82)
Risks

Podcast Episode

Special episode — Obicetrapib: The CETP inhibitor with cardiovascular benefits and potential Alzheimer's prevention

Ep. #384
Longevity

AMA

Biological aging tests, longevity training, emerging therapies, GLP-1 RAs, sun exposure, and more

Ep. #383 (AMA #81)
Longevity

AMA

Longevity optimization through strength benchmarks, VO₂ max targets, nutrition principles, brain health, supplements, GLP-1 RAs, wearables, and more

Ep. #382 (AMA #80)
Medications & supplements

Premium Article

GLP-1 Drugs Fail to Slow Cognitive Decline in Alzheimer’s Disease

Medications & supplements

Free Article

Metformin misses the mark?

Medications & supplements

Premium Article

Navigating the complex relationship between statins, GLP-1, and glycemic control

Exercise

Guest Episode

Women’s health and performance: how training, nutrition, and hormones interact across life stages

Ep. #378 with Abbie Smith-Ryan, Ph.D.
Longevity

AMA

Longevity interventions, exercise, diagnostic screening, and managing high apoB, hypertension, metabolic health, and more

Ep. #376 (AMA #78)
Nutrition

Guest Episode

The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer’s disease, brain injuries, and more

Ep. #375 with Dominic D’Agostino, Ph.D.
All other tactics, tolls, & treatments

Guest Episode

The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences

Ep. #374 with Carole Hooven, Ph.D.
Medications & supplements

Free Article

Cardiovascular benefits of GLP-1 drugs independent of weight loss

Risks

Guest Episode

Thyroid function and hypothyroidism: why current diagnosis and treatment fall short for many, and how new approaches are transforming care

Ep. #373 with Antonio Bianco, M.D., Ph.D.