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#271 – AMA #51: Understanding and improving your metabolic health
“Zone 2 output is arguably the most important functional test we have of metabolic health.” —Peter Attia
More than glycemic control: SGLT2 inhibitors may extend lung cancer survival
A retrospective study offers hope
Can a peptide found in bee stings offer hope for treatment-resistant breast cancers?
Melittin, the main component of honeybee venom, has shown promise as a basis for chemotherapeutic drugs to combat treatment-resistant breast cancer
#268 ‒ Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D.
“There are literally tens of thousands of genetic variants in your genome, and what they mean and whether or not they do anything whatsoever is hard to know.” —Wendy Chung
#267 ‒ The latest in cancer therapeutics, diagnostics, and early detection | Keith Flaherty, M.D.
“Early detection is going to allow our same toolbox of drugs to be massively more effective.” —Keith Flaherty
Successful, early results using CAR T cells to treat an autoimmune disease
Engineered T cells “reboot” the immune system by depleting B cells and autoantibodies
Silencing the alarm on aspartame and cancer
Last month, the International Agency for Research on Cancer designated the low-calorie sweetener aspartame as “possibly carcinogenic,” quickly leading to concern, confusion, and criticism.
#252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting | Rhonda Patrick, Ph.D.
“My perspective has shifted as any scientist that’s following data should… When new data comes out, you have to reassess things.” —Rhonda Patrick
A recent metformin study casts doubts on longevity indications
A new retrospective study contradicts previous evidence of metformin’s potential effects on lifespan extension in a general population, but for real answers, randomized trials are needed.
#216 – Metabolomics, NAD+, and cancer metabolism | Josh Rabinowitz, M.D., Ph.D.
“My big hope is that we’re going to be able to have some combination of directed, metabolic immune supplements and diet that really work with therapy to treat cancer.” —Josh Rabinowitz