#167 – Gary Taubes: Bad science and challenging the conventional wisdom of obesity
“Doing a background analysis is the hard, relentless, rigorous grunt work of science. It’s endless and thankless, because if you do it right, all you’ll do is prove that you were wrong all along.” —Gary Taubes
#140 – Gerald Shulman, M.D., Ph.D.: A masterclass on insulin resistance—molecular mechanisms and clinical implications
“If we can understand insulin resistance, then that’s going to be the best way to fix diabetes, heart disease,. . .fatty liver disease, and slow down cancers.” — Gerald Shulman
#136 – AMA #17: Body composition methods tour de force, insulin resistance, and Topo Chico
“Skeletal muscles are the greatest reservoir that you have for glucose disposal.” —Peter Attia
#118 – Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging
“Our approach is to address serious aging-associated diseases, and if we’re successful, the side effect will be longevity.” — Lloyd Klickstein
#114 – Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies
“I would like to translate what we’ve learned about the role of autophagy in cancer and that involves developing small molecules to inhibit autophagy for cancer therapy.” — Eileen White
#92 – AMA #12: Strategies for longevity (which don’t require a doctor)
“If you are interested in longevity, if you are interested in playing with your great grandkids, you want to prioritize muscle mass. Never in the history of civilization has a 90 year old said, ‘I wish I had less muscle.’” —Peter Attia
Intermittent fasting
Metabolic switching and different forms of fasting.
My nutritional framework
Nutrition is such a loaded topic—almost a religious or political one—so I’m always looking for ways to explain it that are as free from that baggage as possible.
Calorie restriction: Part IIA – monkey studies
Madison, Wisconsin and Baltimore, Maryland: a tale of two studies
Calorie restriction: Part I – an introduction
What does restricting calories have to do with longevity?