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Science of Aging

Learn more about the biology of aging, centenarians, rapamycin, mTOR, ‘anti-aging’ drugs, interventions that target the aging process, and more.

Lessons from centenarians: why prevention of chronic disease is critical

To me, the takeaway for us, as physicians or people who want to have an extra five years of life or 10 years of life… is nothing matters more than prevention of chronic disease. And by the way, you don’t get to prevent it once you have your heart attack. Secondary prevention is not prevention.” – Peter Attia, M.D.

How to engage with your doctor

This audio clip is from ask me anything (AMA) episode #19, originally released on January 18, 2021. If you’re not…

#204 – Centenarians, metformin, and longevity | Nir Barzilai, M.D.

If you prevent aging and age-related disease, you’re going to compress morbidity, too.” — Nir Barzilai

Peter on the four horsemen of chronic disease

This audio clip is from AMA #14: What lab tests can (and cannot) inform us about our overall objective of…

Preventing Atherosclerosis: 2 Fatal Flaws with the “10 Year Risk” Approach

This video clip is from episode #185 – Allan Sniderman, M.D.: Cardiovascular disease and why we should change the way…

Qualys #241 – The genetic gift of centenarians

This episode of The Qualys is from podcast #35, Nir Barzilai, M.D.: How to tame aging, which was originally released on January 7, 2019.

How to Train for the Centenarian Decathlon™

This clip is from “Ask Me Anything” (AMA) episode #05, originally released on April 22, 2019.

#175 – Matt Kaeberlein, Ph.D.: The biology of aging, rapamycin, and other interventions that target the aging process

“I don’t think I will ever understand aging fully. And I don’t think the field will. … But I also believe that we don’t have to understand it fully to be able to have an impact on the biology of aging through interventions.” —Matt Kaeberlein

Funding geroscience; suggested podcast listening

Revisiting the podcast archive

#171 – Steve Austad, Ph.D.: The landscape of longevity science: making sense of caloric restriction, biomarkers of aging, and possible geroprotective molecules

“I never thought [extending the human lifespan] was going to happen because we got better at treating cancer or we got better at preventing heart disease. I always thought it was going to happen because we would develop something … that would fundamentally change the rate of aging. And we haven’t developed that yet. We’ve got a lot of clues and I think we’re getting closer and closer and closer.” —Steve Austad

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