Mendelian randomization and lifetime cardiovascular disease risk.
“Primary prevention is still very much art and not science and probably will be for our lifetime so we’ll have to get used to that.” —Ethan Weiss
“We’re really talking a completely new model, which is actually forcing your way to become a centenarian rather than just sort of gliding your way into it and therefore, I think it’s going to require much more deliberate attention around what your mind and body are doing at that point and time.” — Peter Attia
“If there is one central, common pathway through which we can understand almost all aspects of the deleterious impact of insufficient sleep, it is…an excessive leaning on the fight or flight branch of the nervous system.” — Matthew Walker
Groundhog Day (GD) came and went last month — and sure enough — 2019 has already brought a bounty of emails and Tweets from concerned folks wondering if red meat is going to kill them (again).
“I am on a journey of science, not of advocacy: I’m going to be quite a skeptic.” —Dave Feldman
In other words, statins are not addressing the associated risk in patients with an elevated Lp(a), and this population represents about 25% of those with previous CVD or an indication for statins.
“Anybody interested in this field should probably understand the origins.” —Ron Krauss
I read an interesting paper on fitness, cardiovascular disease (CVD), and coronary artery calcium (CAC) scores from the Cooper Center Longitudinal Study. This paper looked at “generally healthy middle-aged men” and associations between their level of aerobic fitness , CAC scores , and risk for CVD. So why was this interesting to me (and by extension, should you care)?
The most interesting article I read this week was this paper on the NHLBI’s recommendations to reduce Lp(a)-mediated risk of cardiovascular disease.
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