Tag

Neurodegeneration

Aerobic exercise for Parkinson’s disease

The neuroprotective nature of aerobic exercise influences a variety of Parkinson’s disease symptoms, on top of its role in impacting disease risk and progression

Targeting senescent cells for cognitive health

With the recent publication of the first clinical trial of senolytics for AD treatment, popular interest in these drugs has swelled, but is the excitement justified?

Why is it so difficult to determine how nutrition impacts dementia risk?

When it comes to nutrition research, neither observational nor interventional studies have been able to tell the full story. A report by the Nutrition for Dementia Prevention Working Group offers ideas for improving both.

#276 ‒ Special episode: Peter answers questions on longevity, supplements, protein, fasting, apoB, statins, and more

One of the most important things to understand when you are using some sort of intervention is, do you have a biomarker to know if you’re doing it correctly?” —Peter Attia

#271 – AMA #51: Understanding and improving your metabolic health

Zone 2 output is arguably the most important functional test we have of metabolic health.” —Peter Attia

Can treating hearing loss improve cognitive trajectories and reduce dementia risk?

Age-related hearing loss is very common and has long been known to correlate strongly with cognitive decline. A just-published randomized trial sought to evaluate causality in this association. What do we know now?

#257 ‒ Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies, supplements, and more | Tommy Wood, M.D., Ph.D.

If you’re trying to maintain a basic set of cognitive functions, [it is important] to actively work on ways to increase headroom, increase absolute capacity throughout the lifespan. Because at some point capacity will decrease, but you want to push that out as far as you can.” —Tommy Wood

#251 – AMA #46: Optimizing brain health: Alzheimer’s disease risk factors, APOE, prevention strategies, and more

The bottom line here is the earlier you were diagnosed with type 2 diabetes, the higher your risk of dementia.” —Peter Attia

#240 ‒ The confusion around HDL and its link to cardiovascular disease | Dan Rader, M.D.

HDL cholesterol itself is not directly and causally protective against atherosclerotic cardiovascular disease.” —Dan Rader

#236 ‒ Neurodegenerative disease: pathology, screening, and prevention | Kellyann Niotis, M.D.

When you think of brain health, it’s not just the cognitive piece, but it’s the movement piece too.” ‒ Kellyann Niotis

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