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Weekly emails

Understanding science

Randomized controlled trials: when the gold standard leaves you with fool’s gold

If I told you that I read a randomized double-blinded placebo-controlled trial conducted over 5 years and carried out in over 18,000 participants, is there any scenario under which you would not believe it to be an excellent trial?

Mental health

Robin Williams

This Tuesday marks the tragic anniversary of the death of Robin Williams.

Mental models

The power of no

“When you’re saying yes, you’re saying no to something else. Everything in life has a price.” — Ric Elias

Aging

How to find a good doctor

One of the most common questions I encounter, in one form or another, is “How can I find a good primary care physician?” There’s no quick answer, really. I’ve discussed this topic in various podcasts, including our very first AMA, but I’d like to do so again. Start by considering two related questions:   What constitutes a…

Understanding science

The importance of red teams

“The first principle is that you must not fool yourself—and you are the easiest person to fool.” —Richard Feynman

Understanding science

Multiple problems with a study linking proximity to major roads to dementia, Parkinson’s disease, Alzheimer’s disease, and MS

“You miss 100% of the shots you don’t take.” —Wayne Gretzky

Nutritional biochemistry

The red meat and plant-based recommendation wars

Does reducing meat consumption improve health?

Mental models

The pleasure of finding things out

Why do those last few “O”s in a bowl of Cheerios tend to clump together in the middle of the bowl or around the edges?

Diseases

Alzheimer’s disease and glucose metabolism

“In Alzheimer’s Research, Glucose Metabolism Moves to Center Stage.”

Mental models

The killer(s) on the road: reducing your risk of automotive death

How, where, and why do most people die behind the wheel of an automobile? Is there anything we can do to prevent deaths on the road?

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