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#207 – AMA #35: “Anti-Aging” Drugs — NAD+, metformin, & rapamycin
“It’s really hard to know, in my view, how important sirtuins are as longevity factors…If we accept that, then it’s difficult to know [the importance of] activation of sirtuins by NAD as a longevity mechanism.” —Matt Kaeberlein
Peter Attia on Zone 2 and Zone 5 Training
This audio clip was pulled from “Ask Me Anything” episode #12 — Strategies for longevity (which don’t require a doctor). This…
The Drive podcast turns 4
Yesterday marks the four-year anniversary since we launched The Drive. For this week’s newsletter, we’re looking back at some of the most popular episodes over this past year.
#285 – AMA #55: Exercise: longevity-focused training, goal setting, improving deficiencies, managing emotional stress, and more
“Nothing comes close to having a greater impact on the length and quality of your life than your training. And unfortunately, we can’t put it in a pill. You’ve got to be able to do it. There’s no biohack for it.” —Peter Attia
#108 – AMA #13: 3-day fasting, exogenous ketones, autophagy, and exercise for longevity
“I think once people enter that seventh and eighth decade, if they haven’t done a lot of consistent preparatory work in the decades prior, it’s alarming how quickly things go south.” —Peter Attia
#261 ‒ Training for The Centenarian Decathlon: zone 2, VO2 max, stability, and strength | Peter Attia, M.D.
“I would never want anybody to come away from this thinking, ‘I’m too old to do anything about it.’ I think as long as you’re breathing, you have a chance to do something about it.” —Peter Attia
#173 – AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions
“Zone two is a metabolic state. It’s not determined by speed. It’s determined by which energy system you’re requiring and what the equilibrium is.” —Peter Attia
#252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting | Rhonda Patrick, Ph.D.
“My perspective has shifted as any scientist that’s following data should… When new data comes out, you have to reassess things.” —Rhonda Patrick
#248 ‒ OUTLIVE book: A behind-the-scenes look into the writing of this book, motivation, main themes, and more
“You can’t solve or even attempt to solve complicated problems if you aren’t asking the right questions and you don’t have the right frameworks.” —Peter Attia
#217 ‒ Exercise, VO2 max, and longevity | Mike Joyner, M.D.
“The idea is to live a long time and then die quickly with minimal disability.” —Mike Joyner