Fast-breaking without glucose spiking
As I’m coming off of a week of fasting and heading into a week of a ketogenic diet, the timing seems right to address the question of how I break a longer-term fast and the responses that some people get.
Is there an optimal window of time-restricted feeding?
Breakfast like a king, lunch like a prince, and dine like a pauper?
European Vacation
I know I’m not alone in sensing this, as I’ve had this discussion with at least a dozen friends over…
#59 – Jason Fung, M.D.: Fasting as a potent antidote to obesity, insulin resistance, type 2 diabetes, and the many symptoms of metabolic illness
“We think of all these responses, obesity, insulin resistance, and the beta cell failure, as pathologic. They’re actually protective. . .Your body is actually trying to protect itself against the root cause of the problem which is too much insulin, too much glucose.” — Jason Fung
#58 – AMA with sleep expert, Matthew Walker, Ph.D.: Strategies for sleeping more, sleeping better, and avoiding things that are disrupting sleep
“[Sleep] is like that master volume button on a mixing deck that you see in the studio. You can manipulate each one of those dials, or you can go to the far left and just move that one dial…and all of the other levers seem to move with it.” — Matthew Walker
#53 – AMA #6: Fasting framework, vitamin supplementation, antioxidants, time management, problem-solving, and more
“Time is the only truly finite resource that we have. It is also the only unifying, equalizing resource. Meaning, no matter how much wealth or smarts or whatever you have, we are all stuck with the same disappearing thing.” — Peter Attia
The Bad Science Behind ‘Skipping Breakfast’
Bad science is an abomination. Incompetent news reporting on bad science is worse.
#46 – Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease – NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine and more
“People are gonna make a decision to. . . either wait 10 or 20 years until we know something better, or you take the position that you’re going to tinker. And if you’re going to tinker, you’re a lot more successful if you have a working model of what’s going on than if you don’t.” —Chris Masterjohn
The mouse trap: lost in translation?
“The great majority of how we understand disease, and attempt to cure it,” writes Engber, “derives from a couple of rodents.” About 4/5ths of all animal studies reported in biomedical research papers from 1950-2010 were done in rodents (59% in mice, 18% in rats).
Ketones, fasting, and muscle loss
I read an interesting article authored by my friend Dom D’Agostino and his colleagues on the anti-catabolic effects of ketone bodies in skeletal muscle.