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Aerobic & Zone 2 Training

#201 – Deep dive back into Zone 2 | Iñigo San-Millán, Ph.D. (Pt. 2)

You can accomplish very important mitochondrial adaptations and very important metabolic adaptations by exercising one hour.” —Iñigo San-Millán

Protein

Dispelling myths that excess protein intake increases cancer risk

This video clip is from episode #205 – Energy balance, nutrition, & building muscle with Layne Norton, Ph.D. (Pt.2), originally…

Science of Aging

#207 – AMA #35: “Anti-Aging” Drugs — NAD+, metformin, & rapamycin

“It’s really hard to know, in my view, how important sirtuins are as longevity factors…If we accept that, then it’s difficult to know [the importance of] activation of sirtuins by NAD as a longevity mechanism.” —Matt Kaeberlein

Metabolic disease

How metabolic health impacts your ‘optimal’ diet

This audio clip is from “Ask Me Anything” (AMA) episode #36 — all things fruits and vegetables, originally released on June 20,…

Exercise & Physical Health

#218 – AMA #38: Can you exercise too much?

We tend to be far more confident than we turn out to be justified in being.” —Peter Attia

Nutritional Biochemistry

More hype than substance: erythritol and cardiovascular risk

A newly-published study caught public attention by reporting an association between the common sweetener erythritol and increased risk of heart attack and stroke, but there’s more to the story.

Understanding science

#249 ‒ How the brain works, Andrew’s fascinating backstory, improving scientific literacy, and more | Andrew Huberman, Ph.D.

I want to communicate the beauty and utility of biology. I want to do that by being a teacher and a storyteller.” —Andrew Huberman

Medications, Supplements & Other Treatments

Separating substance from nonsense in a study on NMN supplements

A recent randomized trial investigated the effect of NMN supplementation on NAD levels, biological aging, and exercise performance. What can we believe from their results?

Nutritional Biochemistry

#283 ‒ Gut health & the microbiome: improving and maintaining the microbiome, probiotics, prebiotics, innovative treatments, and more | Colleen Cutcliffe, Ph.D.

You start out almost like a blank slate, you get a lot more diverse, and then as we age, you start to lose that diversity and therefore some key functions in the microbiome.” —Colleen Cutcliffe

Medications, Supplements & Other Treatments

#282 – AMA #54: Magnesium: risks of deficiency, how to correct it, supplement options, potential cognitive and sleep benefits, and more

The more deficient you are in magnesium, the more you will be helped by supplementing magnesium.” —Peter Attia

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