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fasting

Science of Aging

#248 ‒ OUTLIVE book: A behind-the-scenes look into the writing of this book, motivation, main themes, and more

You can’t solve or even attempt to solve complicated problems if you aren’t asking the right questions and you don’t have the right frameworks.” —Peter Attia

Metabolic disease

#173 – AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions

Zone two is a metabolic state. It’s not determined by speed. It’s determined by which energy system you’re requiring and what the equilibrium is.” —Peter Attia

Science of Aging

#276 ‒ Special episode: Peter answers questions on longevity, supplements, protein, fasting, apoB, statins, and more

One of the most important things to understand when you are using some sort of intervention is, do you have a biomarker to know if you’re doing it correctly?” —Peter Attia

Fasting

Fast-breaking without glucose spiking

As I’m coming off of a week of fasting and heading into a week of a ketogenic diet, the timing seems right to address the question of how I break a longer-term fast and the responses that some people get.

Cardiovascular Disease

The straight dope on cholesterol – Part IX

In this post we’ll address the following concept: What should you eat to have the greatest chance of delaying the arrival of cardiovascular disease?

Ketosis

Ketones and Carbohydrates: Can they co-exist?

Can you “carb-load” and stay in ketosis?

Cognitive Health & Neurodegenerative Disease

#38 – Francisco Gonzalez-Lima, Ph.D.: Advancing Alzheimer’s disease treatment and prevention – is AD actually a vascular and metabolic disease?

“Everybody goes through this cognitive decline. . .this is a reality. . .but it is possible to intervene before you get into the limbic system problems. . . and that’s going to make the biggest difference.” —Francisco Gonzalez-Lima

Sleep

#45 – AMA #4: sleep, jet lag protocol, autophagy, metformin, and more

“Every day in the human body, some 10 billion cells die and are replaced by new cells.” —Nick Lane

Ketosis

#120 – AMA with Dom D’Agostino, Ph.D., Part II of II: Ketosis for cancer and chronic disease, hyperbaric oxygen therapy, and the effect of ketosis on female health

“The function of the mitochondria and mitochondrial health are the ultimate mitigator of neurodegenerative diseases…just by reducing the potential for reactive oxygen species related damage.” — Dom D’Agostino

Preventing Chronic Disease

#134 – James O’Keefe, M.D.: Preventing cardiovascular disease and the risk of too much exercise

If exercise were a drug, it would be the best drug we have for preventing heart disease . . .. But like with any drug, you’ve got to get the dose right.” — James O’Keefe

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