Category

Preventing Chronic Disease

One of the foundational lessons we can take away from studying centenarians — those who have lived to the age of 100+ — is that if you want to live longer, you have to live longer without chronic disease, not live longer with chronic disease. Unfortunately, our current healthcare system is primarily geared toward helping you live longer once you develop chronic disease. This, of course, is the opposite of the approach I take with my patients.

Over 80% of deaths in people over 50 who do not smoke can be grouped into 4 main categories, what I like to call the four horsemen of chronic disease. These are: (1) atherosclerotic disease (comprised of cardiovascular disease and cerebrovascular disease), (2) cancer, (3) neurodegenerative disease (Alzheimer’s disease being the most common), and (4) metabolic disease (a spectrum of everything from hyperinsulinemia to insulin resistance to fatty liver disease to type 2 diabetes).

We have five main longevity tactics at our disposal to affect our longevity: (1) exercise, (2) sleep, (3) nutrition, (4) medications & supplements, and (5) distress tolerance. Below is a collection of podcasts and articles discussing how we can use these tactics to mitigate, prevent, and reverse chronic disease.

“Not everybody dies from atherosclerosis, but… everybody dies with it.” — Peter Attia

Several studies have examined the effects of both maternal diabetes and maternal metformin exposure on offspring, but prospective fathers have received comparatively little attention. A recent study sought to change that.

This video clip is from episode #185 – Allan Sniderman, M.D.: Cardiovascular disease and why we should change the way we…

This video clip is from episode #185 – Allan Sniderman, M.D.: Cardiovascular disease and why we should change the way we…

This video clip is from episode #185 – Allan Sniderman, M.D.: Cardiovascular disease and why we should change the way…

This audio clip is from episode #202 – Peter on nutrition, disease prevention, sleep, and more, originally released on April…

This clip is from episode #202, Peter on nutrition, disease prevention, sleep, and more, originally released on April 11, 2022….

“I really think that in 10 years we’re going to basically be using designer-based immunotherapies to eradicate most solid organ metastatic cancers.” —Peter Attia

Diabetes was only the 8th-leading cause of death in 2020. Can it really be possible that diabetes is so “harmless” relative to the other major chronic diseases, or are the CDC reports only the tip of the iceberg?

This audio clip is from episode #37 with Zubin Damania, M.D., originally released on January 21, 2019.

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