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Alzheimer

Centenarians

#204 – Centenarians, metformin, and longevity | Nir Barzilai, M.D.

If you prevent aging and age-related disease, you’re going to compress morbidity, too.” — Nir Barzilai

Cognitive Health & Neurodegenerative Disease

Why does Alzheimer’s disease affect more women than men?

This clip is from episode #138 – Lauren Miller Rogen and Richard Isaacson, M.D.: Alzheimer’s disease prevention—patient and doctor perspectives,…

Fasting

#114 – Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies

“I would like to translate what we’ve learned about the role of autophagy in cancer and that involves developing small molecules to inhibit autophagy for cancer therapy.” — Eileen White

Cognitive Health & Neurodegenerative Disease

Peter on Alzheimer’s disease prevention and the latest on APOE4

This clip is from episode #202, Peter on nutrition, disease prevention, sleep, and more, originally released on April 11, 2022….

Metabolic disease

#271 – AMA #51: Understanding and improving your metabolic health

Zone 2 output is arguably the most important functional test we have of metabolic health.” —Peter Attia

Exercise & Physical Health

#176 – AMA #27: The importance of muscle mass, strength, and cardiorespiratory fitness for longevity

“If you have the aspiration of kicking ass when you’re 85, you can’t afford to be average when you’re 50.” —Peter Attia

Medications, Supplements & Other Treatments

#10 – Matt Kaeberlein, Ph.D.: rapamycin and dogs — man’s best friends? — living longer, healthier lives and turning back the clock on aging and age-related diseases

“I believe that rigorously demonstrating that we can increase healthspan and lifespan in pet dogs will be a huge step toward gaining the support and credibility that the field needs.” —Matt Kaeberlein

Science of Aging

#175 – Matt Kaeberlein, Ph.D.: The biology of aging, rapamycin, and other interventions that target the aging process

“I don’t think I will ever understand aging fully. And I don’t think the field will. … But I also believe that we don’t have to understand it fully to be able to have an impact on the biology of aging through interventions.” —Matt Kaeberlein

Sleep

#48 – Matthew Walker, Ph.D., on sleep – Part II of III: Heart disease, cancer, sexual function, and the causes of sleep disruption (and tips to correct it)

“If there is one central, common pathway through which we can understand almost all aspects of the deleterious impact of insufficient sleep, it is…an excessive leaning on the fight or flight branch of the nervous system.” — Matthew Walker

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