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#194 – How fructose drives metabolic disease | Rick Johnson, M.D.
“Fructose turns out to have been meant to be this wonderful system for survival, but in our culture with the amount of sugar in foods that we are eating (that either provide sugar or can be turned into fructose), this pathway has become hazardous.” —Rick Johnson
When does heart disease begin (and what this tells us about prevention)?
Before I get into this post I want to lay a few things out.
#271 – AMA #51: Understanding and improving your metabolic health
“Zone 2 output is arguably the most important functional test we have of metabolic health.” —Peter Attia
#293 – AMA #57: High-intensity interval training: benefits, risks, protocols, and impact on longevity
“You want to broaden your portfolio of training.” —Peter Attia
#140 – Gerald Shulman, M.D., Ph.D.: A masterclass on insulin resistance—molecular mechanisms and clinical implications
“If we can understand insulin resistance, then that’s going to be the best way to fix diabetes, heart disease,. . .fatty liver disease, and slow down cancers.” — Gerald Shulman
#201 – Deep dive back into Zone 2 | Iñigo San-Millán, Ph.D. (Pt. 2)
“You can accomplish very important mitochondrial adaptations and very important metabolic adaptations by exercising one hour.” —Iñigo San-Millán
#166 – Patricia Corby, D.D.S.: Importance of oral health, best hygiene practices, and the relationship between poor oral health and systemic disease
“You can maintain optimal oral health just by brushing teeth, by flossing really well, and having good nutrition.” —Pat Corby
#147 – Hussein Yassine, M.D.: Deep dive into the “Alzheimer’s gene” (APOE), brain health, and omega-3s
“What’s important is in science, you always have to be skeptical and you always need to find whether any particular study can be replicated or not before you make strong recommendations and adopt any drastic change and how you are consuming certain things, whether it’s a medication or a diet or a supplement.” — Hussein Yassine, M.D.
#218 – AMA #38: Can you exercise too much?
“We tend to be far more confident than we turn out to be justified in being.” —Peter Attia
#257 ‒ Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies, supplements, and more | Tommy Wood, M.D., Ph.D.
“If you’re trying to maintain a basic set of cognitive functions, [it is important] to actively work on ways to increase headroom, increase absolute capacity throughout the lifespan. Because at some point capacity will decrease, but you want to push that out as far as you can.” —Tommy Wood