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Preventing Chronic Disease

One of the foundational lessons we can take away from studying centenarians — those who have lived to the age of 100+ — is that if you want to live longer, you have to live longer without chronic disease, not live longer with chronic disease. Unfortunately, our current healthcare system is primarily geared toward helping you live longer once you develop chronic disease. This, of course, is the opposite of the approach I take with my patients. 

Over 80% of deaths in people over 50 who do not smoke can be grouped into 4 main categories, what I like to call the four horsemen of chronic disease. These are: (1) atherosclerotic disease (comprised of cardiovascular disease and cerebrovascular disease), (2) cancer, (3) neurodegenerative disease (Alzheimer’s disease being the most common), and (4) metabolic disease (a spectrum of everything from hyperinsulinemia to insulin resistance to fatty liver disease to type 2 diabetes).

We have five main longevity tactics at our disposal to affect our longevity: (1) exercise, (2) sleep, (3) nutrition, (4) medications & supplements, and (5) distress tolerance. Below is a collection of podcasts and articles discussing how we can use these tactics to mitigate, prevent, and reverse chronic disease.

Lack of context may fuel spread of unintended consequences

A recent study on diet and prostate cancer suggests we need to be more careful communicating and interpreting information.

A big predictor of heart disease risk that most doctors don’t screen for

The most interesting article I read this week was this paper on the NHLBI’s recommendations to reduce Lp(a)-mediated risk of cardiovascular disease.

Studying Studies: Part I – relative risk vs. absolute risk

Reporting relative risk values alone can be inappropriate and misleading for the individual and the public.

Is Type 2 Diabetes Reversible at Scale?

If you’re reading this, you probably know that I’m obsessed with longevity.

When does heart disease begin (and what this tells us about prevention)?

Before I get into this post I want to lay a few things out.

Is there a way to exploit the metabolic quirk of cancer?

Can we starve the disease?

The War on Cancer

How are we faring in the War on Cancer?

Is a Mediterranean diet best for preventing heart disease?

This week an article titled Primary Prevention of Cardiovascular Disease with a Mediterranean Diet was featured in the New England…

How did we come to believe saturated fat and cholesterol are bad for us?

There aren’t too many topics that really get me riled up anymore.  I’m too old and too busy to care…

The straight dope on cholesterol – Part IX

In this post we’ll address the following concept: What should you eat to have the greatest chance of delaying the arrival of cardiovascular disease?

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