Ask Me Anything

If you have a question for Peter that you want answered on one of his AMA podcasts, this is the place to ask it.

What are your thoughts on the widespread use of statins?

December 9, 2018

We know that simply lowering LDL does’nt necessarily confer mortality benefits , otherwise drugs like ezitimibe would work. Statins on the other hand have some anti inflammatory effect on endothelial cells in addition to the LDL lowering effect and has shown mortality benefits. Is there any reason behind the anti statin sentiment that seems to…

For those working on becoming fat adapted by cycling in and out of a ketogenic diet, are there any special considerations for people who had their gallbladder removed?

December 9, 2018

I’m wondering because bile from the gallbladder helps with digestion of fat, and my gallbladder has been removed. This means the bile from my liver has no reserve to promote better digestion after a keto meal. Rather, I always have access to the same small amount of bile. My concern is that this could mean…

I am getting a lot of value out of your podcast and emails. Would you ever consider something similar to what Rhonda Patrick and Sam Harris are doing with respect to crowdfunding? Thanks!

December 9, 2018

What are the long term effects of estradiol after total hysterectomy

December 9, 2018

I’ve been on estradiol for 12 years (post hysterectomy) and hope to never discontinue using it. However, I get concerned about the long term health effects. Not a single physician seems to be able to answer whether this is a terrible idea or not.

Hi Dr. Attia, I recently began devouring your content and have come to the point where you have advocated for the Keto diet yet now admit you no longer follow it. Do you still believe it will lower your risk o

December 9, 2018

Hi Dr. Attia, you have been a long time advocate for the Keto diet in response to your increased risk of heart problems, could you address your change in eating habits? I respect your reasoning in making the change, but could you quantify your increased risk in making the switch?

Two part question: a) could you comment on the recent paper by Seidelmann et al., in Lancet on the discovery that there appears to be a 50-55% carbohydrate dietary sweet spot and how that impacts your views on the ketogenic diet (if it does), and b) please comment how you, Bob Kaplan, and your team critically review a paper like that (yes, a lesson in critical thinking). Thank you. (Seidelmann, S. B., Claggett, B., Cheng, S., Henglin, M., Shah, A., Steffen, L. M., … & Solomon, S. D. (2018). Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis. The Lancet Public Health, 3(9), e419-e428).

December 9, 2018

Thank you.

In your interview with Dr. Rhonda Patrick, you speak about the importance of keeping IGF and MTOR in check with nutrition and a focus on macronutrients. You also mention how every body is different regarding the percentage of each of the macronutrients. If I know how much lean muscle mass I have, and I have the OGTT results, how do I go about in determining the percentages of protein, carbohydrates, and fat my body would benefit most in order to keep IGF and MTOR in check?

December 9, 2018

How will I know if my question will be chosen to be answered during an AMA sessions? Thank you

I am experiencing headaches after transitioning from keto to a slow carb diet. Have you encountered these symptoms?

December 9, 2018

I’m a vegetarian and a foodie who likes variety in my food. Staying on a keto diet has been very difficult for me. After 4-6 months of nutritional ketosis, I tried to transitionto a 80-100g slow carb diet. This transition hasn’t been a pleasant experience for me. I experience severe head and neck aches (…

Are there any additional benefits to intermittent “dry fasting” where one abstains from drinking water in addition to not eating?

December 9, 2018

I have hemochromatosis and was looking at taking SARMS LGD 4033 and S4. Do they raise ferritin levels?

December 9, 2018

Is there any studies or documentation? Thank you for your time Peter and love the Podcast.

Hi Peter. Do you have any insights on the potential for BCAA’s to have a negative impact on insulin sensitivity?

December 9, 2018

Whilst results from a simple google search will return the many metabolic benefits around BCAA consumption from a diet with sufficient protein and/or dietary supplement of BCAA, a number of reports suggest that BCAA’S may result in insulin resistance. In addition, one particular referenced article suggests that by way of lactose and protein in dairy…

If a lean mass hyper-responder has elevated LDL due to increased synthesis and absorption, would a single agent treatment targeting absorption have a significant impact; ie zetia/questran? And would SNP suggesting increased risk for myopathy with statin use influence your decision.

December 9, 2018

Can you shed more light on the decision to move away from engineering in pursuit of further education?

December 9, 2018

Was the decision easy for you? What was your self talk/ thought process to walk away from your undergrad field of study?

Hashimotos and multivitamin supplementation

December 9, 2018

Hi Peter – for patients with Hashimotos, do you suggest patients stay away from multivitamins with iodine? Thank you

Could you tell us about your position in respect to Comprehensive Thyroid Testing vs Basal Body Temperature Testing for Thyroid Function? And possibly how you diagnose, treat, & support hypothyroid clients?

December 9, 2018

Those who practice the Broda Barnes Basal Temperature Test state that testing the Free T3 and Free T4 and even TSH are 1 or 2 steps removed from the final target site (meaning – measuring thyroid activity at the tissue level). With the idea that the basal body temperature tells us more about the thyroid…

Top 5 blood tests everyone should ask their doc for?

December 9, 2018

So many of the tests you discuss are not a part of a basic blood panel for healthy people but seem to offer important information. For example, each year my family doc orders a basic cholesterol panel but that’s it, and a basic CRP rather than HS-CRP. I’ve never had a homocysteine test and yet…

What do you believe should be the lifestyle/diet of a person aiming for an optimal gut microbiome?

December 9, 2018

Wouldn’t MSG (as found within bouillon) have a negative effect on fasting insulin levels?

December 9, 2018

Research has shown MSG to be quite insulinogenic.

What’s your take on the use liver-selective thyroid receptor beta agonists for treating Hypercholesterolemia, NAFLD, NASH, and related diseases? Many trial-stage medications have shown promising Phase 2 results (e.g., VK2809 by Viking Therapeutics and MGL-3196 by Madrigal ) ?

December 9, 2018

This seems to show an link between thyroid hormones and liver functions related to fat and cholesterol.

How do we keep arthritis at bay as we age? Any specific routines, supplements etc.. that you could point at?

December 9, 2018

Almost everyone over 60 in my family suffer from knee pain. Several of them have had knee surgeries and the amount of pain that they are enduring is already making me very nervous as to what future has in store for me. What can I (in my mid thirties) and people like me, do to…

Does curcumin supplementation dull the necessary inflammatory post-exercise?

December 9, 2018

The literature (I’ve reviewed) suggests recovery time is quicker when taking curcumin, however, this may dampen the acute inflammatory response necessary for hypertrophy. This suggests to be similar to ibuprofen, also a COX-2 inhibitor. What’s the trade off here? Systemic inflammation v Muscle Development. Framing this with the view of longevity. Cheers 🙂

Hi Peter, what are your thoughts on recent studies connecting Keto Diets to shorter lifespans? https://www.bluezones.com/2018/09/news-study-finds-low-carb-or-keto-diets-could-lead-to-shorter-lifespan/

December 9, 2018

Peter what are your thoughts on different medications to prevent bone loss as you age ?

December 9, 2018

The Sleep Remedy you take has 4000 IU of vitamin D3. Since fat soluble, I read half life is 15 hours. According to Rhonda Patrick there’s an upside down U with a sweet spot at 40-50 mg/dL in blood stream. Do you regularly test your levels to ensure you’re in the sweet spot? Seems like taking this Sleep Aid every day might put you on the downward part of that U curve.

December 9, 2018

I have a hard time sleeping at length and take a sleep aid every now and then. Doc’s Sleep Remedy piques my interest but the amount of vitamin D is quite a bit. I live in a sunny climate and also get D3 from other supplements I take. The whole topic of vitamin D is…

When you reduced saturated fat in your ketogenic diet patients who were hyper LDL responders, did you allow MCT oil or C8? What is your feeling on allowing these in a hyper responder? Patient has Parkinson’s and C8 helps with symptoms.

December 9, 2018

Fasting Question? Why not fast with salt water i.e. electrolytes rather than just plain water? So you maintain all your electrolytes?

December 9, 2018

Given your medical background and amazing propensity to digest data, do you have an opinion on flu vaccines? Should we all get vaccinated?

December 9, 2018

Hi Peter, could you elaborate on NuSI? What it was, how it performed, the challenges of nutrition science and lessons learned?

December 9, 2018

Appreciate your work, personality and the open invitation to the nerd safari.

Do you plan to have an AutoImmune expert on the podcast? Alternatively, are you planning a deep dive, or Nerd Safari, into Autoimmune disorders?

December 9, 2018

FTO and saturated fat, how bad is it and what to do about it?

December 9, 2018

What do you think about how the FTO gene plays into whether or not to consume animal fats? I have a FTO mutation and have been eating saturated fat mainly in the form of butter and ghee. I probably average a couple of tablespoons per day between the two. I’ve heard Dr. Rhonda Patrick express…

As I get older I notice it takes much longer to recover from workouts. I want to keep muscle mass (or even gain some). What’s the longevity approach to workout recovery? Supplements? El natural?

December 9, 2018

Does the longevity approach skirt anabolic steriods, DHEA, HGH, or TRT? Or are there useful applications for these tools? This is really about HRT isn’t it, so if you can include some insight to recovery when you get to that podcast that’ll be great…thanks. Of course I expect women’s HRT podcast is first, as it…

How do you best treat patients with elevated blood plant sterols (patients that are hyperabsorbers)? Any other methods other than Zetia like a certain diet or avoidance of certain vegetables?

December 9, 2018

My lipidologist/Cardiology friend on the way to ACL in Austin was quite concerned about my lipids and plant sterols on my Truehealth labs. We are going to meet soon to discuss my situation. He made the comment that he never saw a lp(a) that high 234 nmol/L. My other lipids were concerning also LDL-C 186,…

Hey Peter, what is your opinion on the recent keto-carnivore or carnivore diet and what the possible causes of the “benefits” being reported?

December 9, 2018

Rhonda Patrick suggested it mimics fasting. Keto-carnivore – animal products only (limited dairy if tolerable) Carnivore- beef, salt water it seems to be working for a lot of people, and for me personally it has improved my mood, sleep, focus, digestion, etc after a month and a half.

What specifically is the concern about circulating glucose?

December 9, 2018

What is the specific cause for concern when blood glucose is elevated? I.e. if my blood glucose is routinely above 100 but my markers of inflammation and other health indicators (blood pressure, etc.) are within healthy ranges, is circulating glucose itself a cause for concern?

What would your protocol be if you were to get a late-stage cancer diagnosis?

December 9, 2018

Great conversations with Dr. Dayspring. One quick stay to day practical question. When people cite Minnesota feeding experiments and the work of Ancel Keys and say dietary intake of Cholesterol diets not increase serum total cholesterol, doest take into account what baseline we start with? Those businessmen in the Minnesota feeding experiments started at a baseline of ~250 and higher. What if the baseline TC is in the 140-150 range? Thank you?

December 9, 2018

is there a way to prevent chills and cold hands when doing daily IF

December 9, 2018

I fast 8pm -12pm most days following the leangains “Early morning fasted training” protocol (https://leangains.com/the-leangains-guide/). Things are working pretty well with very little struggle. One challenge is that I get chills and painfully cold hands in the mornings after I work out. Is there any way to manage this?

What are your thoughts on different peptides like BPC _157

December 9, 2018

Can you provide details on the weight loss program created for Tom Dayspring?

December 9, 2018

Apo E 2/4 genotype

December 9, 2018

Hi Dr. Attia, I’m really enjoying your series with Dr Dayspring and I also the recent episode with Dave Feldman. During your discussion with Feldman you alluded to Apo E4 as a risk factor for atherosclerosis (Alzheimer’s also as everyone knows) and Apo E2 typically is seen as protective for these. I had my Apo…

What would be your additional protocols for someone on Testosterone Replacement Therapy? I inject 1/2 cc every 7 days.

December 9, 2018

Enjoy the podcast. My initial Dr. suggested and prescribed a daily low dose aspirin, a vitamin D supplement (initially D2, but since changed to D3) and a B12. The initial Dr. quit his practice and I’ve moved the prescription over to my family Dr. My family Dr. is very skeptical of the dosage. I donate…

What’s your take on dietary choline intake (eggs, etc.) and TMAO? Whast t do you make of the fact many patients are choline deficient? What are the implications for patients with MTHFR mutations.

December 9, 2018

https://www.nejm.org/doi/full/10.1056/NEJMoa1109400?query=featured_home Many many foods (including fish) seem to increase TMAO… Ponder ponder

Essential Lipid Labs and Reference Ranges for Patients

December 9, 2018

It would be so helpful for patients to have list of the important lipid lab tests to do as part of a general health assessment along with the reasons for doing them, reference ranges, where to get them, etc. Armed with that information we could have a more productive conversation with our physician.

Can a ketogenic diet help at all with maintaining vitamin D levels?

December 9, 2018

Hello Peter, Love your podcast! Keeps me motivated to stay healthy! Your podcasts about eating cake with your family cracked me up. It keeps me smiling when I’m the only one in my family choosing to not eat bday cake for my bday, or any other time for that matter. Here’s the deal: In my…

Have you looked into HGH 30x homeopathic trans-dermal “Somaderm” ingredients for efficacy? What is your position on homeopathy & trans-dermal in general?

December 9, 2018

What do you think? I appreciate and value your opinions Peter! This may be the wrong platform to be asking this question, please redirect as needed, thank you… DD in WA https://newulife.com/VITALITYyouRS Home

Hi Peter. I am 23 yrs old and have for my entire life had visibly swollen lymph-nodes. Specifically in my neck (posterior cervical I believe) and in my groin. Periodically I will also get painful occipital lymph node swelling and arm pit swelling. The chronically swollen nodes aren’t painful and can be pushed around. No doctors have given me a clear answer as to what is going on. Any help you can provide is greatly appreciated. Thank you kindly, Jesse.

December 9, 2018

Physician in Denver

December 9, 2018

Any recommendations for primary care docs in Denver metro area?

Do a podcast on thyroid.

December 9, 2018

There are many endo’s that don’t even consider T3. There is so much information about thyroid issues. Everyone has a cure. My hope would be a multi-episode cast similar to your lipo themed cast.

Can you provide a sample high monounsaturated menu for those with high LDL-P counts but wishing to maintain a ketogenic diet.

December 9, 2018

What is your take on eating fats considering fatty acids supposedly are the cause of diabetes or do you think just high insulin levels cause diabetes

December 9, 2018

Can ketogenic diet/fasting cause permanent insulin resistance

December 9, 2018

I have been following a not too strict ketogenic diet for over a year and experimented with Intermittent Fasting for a little over a month. Last week I noticed that my fasting BG levels are in the 100 -110 mg/dl range. My last HbA1c level (4.9%) and FBG (76-80 mg/dl) prior to starting the ketogenic…

What do you think of the scientific strength claims behind John Jaquish’s x3bar variable resistance product?

December 9, 2018

https://www.youtube.com/watch?v=1Ewn0f7LY7c x3bar.com https://youtu.be/XcUw6cXrIVI

Re: extended fasting -Highlight potential risks of long term fasting (ex. Refeeding syndrome, mineral/vitamin depletion or imbalance, etc.) -minimum metrics to monitor regularly(during fast), glucose, ketones, BP, HR, etc. – Dangerous levels/patterns of concern? -red flags/warning signs to discontinue fast. -additional supplements during refeed?

December 9, 2018

I’ve listened to hundreds of hours of podcasts and a lot of info on fasting but haven’t heard anything specific regarding significant risks. The first 2-4 days of refeeding following a recent 7day fast I experienced significant post prandial fatigue and irregular/elevated heart beat. A bit of research made me realize potential serious risks I…

Hi Peter, do you know of any studies that connect constantly increased level of CO2 and metabolism, as well as developing dementia?

December 9, 2018

Two years ago we have bought CO2 detector for our house and it’s a big challenge to keep CO2 level below unhealthy level. AC and energy savings and all that… We are going to install ventilation system, but this is not discussed widely. Do you think constantly living with elevated CO2 contributes to metabolic issues?

How do you increase your deep sleep. My Oura is telling me I consistently get 2-3% a night. My brain not getting cleared!! I worry.

December 9, 2018

Previous question: I get only 3 minutes of deep sleep per night on my Oura

December 9, 2018

I submitted previous question same thing, but am getting only a couple of minutes of deep sleep a night, not a few percent Oura says. 1%

Have you heard of NOSH-aspirin? Its anti cancer effects look great

December 9, 2018

How do we interpret the recent results from the ASCEND trial for primary prevention? Should we be putting our patients with elevated LP (a) on Aspirin? (amazingly not addressed in the 8 hours with Dr. Dayspring…it was awesome and did cover everything else I believe!!

December 8, 2018

How extensively have you looked at Ayurveda?

December 8, 2018

Ive found great benefits from applying concepts from Ayurveda into my life. Considering that the word translates to mean “life knowledge” and deals directly with extending the longevity of the human system I feel that it’s something you might be interested in.

Peter, can you please comment on the lifespan and health span benefits of socializing and actively participating in one’s community? By some recent articles, effect sizes are huge and on the order of not smoking. Eager to hear your critical review of this topic. Thanks, Peter, and keep up the great work!

December 8, 2018

I was so impressed with the Dayspring & Krause podcasts that I want to see a likeminded MD like you or someone you recommend. Have you set up any kind of referral network? I live in Portland, Oregon.

December 8, 2018

Hello Peter, what are you advice to consolidate the endothelium and avoid the infiltration of LDL particles ? what can protect the glycocalyx ?

December 8, 2018

NO donors like beets ? catechines/flavonols from tea/coffee ? (In critical care we now know that massive fluid infusion are bad…)

Peter, thanks for your episodes on Alzheimer’s prevention. Can you and your team please review the latest BACE1 inhibitor data (Merck, Lilly, etc.; recent “emergency” session at the CTAD conference) and posit whether you think dose, MOA, patient demographics/disease window, and/or other factors contribute to the toxicity and/or lack of efficacy in these drugs? Perhaps you could interview one of the academics who specialize in and/or lead these trials?

December 8, 2018

Is eating only one or two large meals while intermittent fasting putting strain on postprandial insulin or your digestive system/microbiome since the meals can be very large to maintain total daily caloric intake (especially for active people)?

December 8, 2018

How can I and my family become a patient at Attia Medical?

December 8, 2018

thank you – Jonathon

What’s your opinion on this new meal replacement Huel. Seems to be higher quality to Soylent and some others I’ve seen previously. Thanks for all the info you provide on the podcast.

December 8, 2018

On a keto diet: Counting total carbs vs total carbs minus dietary fiber

December 8, 2018

So, it seems as though the common belief is that TC – DF gives you the number of carbs you need to count to stay in ketosis. I’m guessing that is because of the body’s insulin response being less when DF is present. Having type 1 diabetes, if I try to give myself insulin based…

How to increase deep sleep? Does the Tom Dayspring of sleep exist?

December 8, 2018

Many of us are using to our OURA ring to measure our sleep quality. Now we need a sleep podcast like the lipids podcast with Tom Dayspring. So far my attempts have been like my golf swing, I get a great nights sleep and think I have it figured out, and the next day I…

What are the main neurotransmitters and if taking precursors to them is actually effective?

December 8, 2018

Thank you for the immense about of information you provide. As someone with two ApoE4 genes, I appreciate your candid information about balancing the risks and rewards of treatments.

Why did you stop Keto, high LDL?

December 8, 2018

There is evidence that a LCHF diet increases LDL. Is this true if the fats are predominantly PUFA and MUFA? If so, what is the mechanism for the increase. I have seen studies pointing to SFA impact on enzymes that regulate LDL receptors in the liver. Is this the problem or do too many consumed…

How do you interpret your Oura Ring data? I heard you mention that you delve more into the numbers rather than the “scores” the app gives you. Can you explain what you track and what you look for?

December 8, 2018

Please address rejuvenating the Thymus and if you think it will benefit longevity such as the experiment Greg Fahy is currently performing.

December 8, 2018

The Thymus is the origin of our T-cells, Dr. Fahy’s has shown the Thymus can be rejuvenated he is currently performing a study which I hope will give us better information on whether the rejuvenated thymus will produce intelligent lymphocytes. The third question submitted on this subject.

Thoughts on turmeric?

December 8, 2018

Thoughts on what people would consider, “natural supplements”? Mushroom matrix? Flax? Chia seeds?

My question is what is the ideal dose (high, mid, low) of statin (I take rosuvastatin) for one to get the maximum benefits and avoid some of the side effects (myopathy, liver enzymes)?

December 8, 2018

There seems to be many pleiotropic benefits to taking statins based on years of research and RCTs. There also seems to be a number of detrimental side effects at higher doses of statins and not a ton of benefit in altering MACE comparatively to lower dose statins. I am looking at this kind of from…

My BMI is in the ¨normal range¨, close to the Lower level. I want to gain weight while doing a healthy diet being Paleo or Keto. What advice would you give to people trying to gain some weight 5 or 7 KG of muscle while being healthy.

December 8, 2018

I am 168cm tall, weight 56Kg, I would like to be in the 60 to 62 Kg weight range. I am a developer, but I try to be active, stand up usually and do some stretches and simple exersises every 2 hours. I do HIIT 2 times a week and I also try to lift…

Drastically reducing carbohydrate intake has altered the landscape of my hunger: before the change in my diet hunger was a “non-maskable interrupt” that demanded I stop activities to eat. Now, hunger is a Post-It note on my desk, something I’m inclined to do in due time. Is this a common experience and, if so, what is the likely explanation for the change in physiological hunger response? Is it due to an alteration/mix in gut bacteria and their influence on us?

December 8, 2018

My before diet was composed of plenty of bread, pasta, etc and I identify with your “I never met a carb I didn’t like” statement. Now I restrict my diet to 50g of carbs daily, typically, but feel comfortable cheating if I want. When I cheat, it’s not uncommon for my hunger to be more…

Do you recommend a focused DNA test to determine an individual’s genotype to understand which athrogenic genetic conditions may exist? If so, can you recommend a test?

December 8, 2018

My doctor has never suggested this (genetic testing) but it seems prudent to determine if there’s an underlying genetic predisposition to atherosclerosis so I can determine if there’s any therapy needed. Am I barking up the wrong tree?

I’m interested in your comments regarding the bioethics of gene therapy in cases where a clear cause of disease has been determined. For example, a new therapy can be used to rewrite faulty genes in infants with X-SCID — what if we could use the same technique for an infant that would alter the PCSK9 makeup, thereby preventing hypercholesterolemia or even to promote hypocholesterolemia and prevent CHD?

December 8, 2018

Since total exposure to LDL-C is a key predictor in CHD, wouldn’t it make sense to “inoculate” infants? Vaccines are widely (although not completely, unfortunately) accepted — do you believe the same could be true for genetic alterations? If they are beneficial, could they be sold to the public? From a scientific, evolutionary perspective if…

Whats your thoughts of metformin supplementation for longevity/prevention of alzheimers/cancers?

December 8, 2018

Should non diabetics, with the APOE4 gene individuals be cautious taking metformin? would metformin put you more at risk. I read conflicting studies

Elevated fasting glucose AM while in keto

December 8, 2018

I have been on keto for a month and have have had glucose blood reading of 108-124. Also, do Prolon 5 days fast and had elevated reading during 4 of the 5 days. One day at 84. My normal med diet glucose is 84-98. Is this normal for some folks? Is this insulin sensitivity?

Would be interested to know what happened to your lymphocyte count during your fast? Valter Longo found reduced lymphocytes during FMD and regeneration during refeeding. Could this be one of the markers of autophagy you are looking for?

December 8, 2018

Hi Peter. I’ve been diving into Electromagnetic Fields and if/how they affect human biology. Seeing as the radiation levels have increased massively in only the last 10 years. What are your thoughts on the subject and should we be worried?

December 8, 2018

Can you speak about your modified version of Dr Valter Longo’s fasting-mimicking diet (FMD) that you had Dr Tom Dayspring using?

December 8, 2018

Vaulter Longo strongly recommends against fasting over 70. What’s your take on fasting, ketosis given that IGF-1 and HGH levels drop off so much in the elderly.

December 8, 2018

I’m 75 so I have a lot of skin in the game, as they say (y’all going to be here soon). I’m fairly fit and have been low(ish) carb for 20 years – since reading the first Zone Diet book. There doesn’t seem to be much research in this area.

Watch and Writing Devices!

December 8, 2018

Thanks for sharing your love of the Seiko Cocktail Automatic Watch! Would love to hear more of your fascination with these “devices”, I love watches too! Fine Pens pair with Watches too, do you collect Pens? Would love to hear more. David

When would be the best time to supplement magnesium during a fast?

December 8, 2018

I take a magnesium supplement in the first 12~ hour window of my fast but I’ve heard of greater benefits of taking it longer into my fast (+24h)

Ketosis for Type I diabetic

December 8, 2018

I have a family member who is a type 1 diabetic with a continually advancing weight and insulin resistance problem…is there any way to safely get into and stay in ketosis without ketoacidosis or other complications with a type 1 patient? And if there is, how does one dose for insulin in a state like…

Where do i find the answers to AMAs? Only on the AMA podcasts? Also where do i find the podcast notes? Thanks!

December 8, 2018

Supplements to take while preg to optimize baby’s growth and health?

December 8, 2018

Did you have your wife do a certain protocol? I personally have pcos and endometriosis. I am very fit (have done bodybuilding shows and maintain healthy muscle- naturally) Iv had many surgeries to remove cysts and untwist my ovaries. I am doing IVF now (am 29 yrs old) any suggestions will be helpful! Love your…

Recommended books: trauma and healing

December 8, 2018

Peter, I am beyond grateful for your podcast with Paul Conti — thank you. Earlier this month, over my 33rd birthday, I completed the Hoffman Process program in Northern California. While facing childhood trauma is painful, I’ve found the work to be the most healing and energizing of any method I’ve explored to date. Between…

How far are we before nutrition becomes a more central part of any doctor’s advice/prescription to patients?

December 8, 2018

Out here in India I am hearing the same standard advice of eating throughout the day, low fat, low sodium diets etc. Even things such as reversing diabetes (type 2) are things that docs aren’t willing to discuss.

What resources would you suggest for laymen to learn more about nutrition and how to build our diets and lifestyle in countries like India?

December 8, 2018

We typically don’t have easy access to a variety of good ingredients. Even if we do it is not cost effective. Any suggestions on credible resources that can help with alternatives or build sustainable lifestyles would be much appreciated. Cheers

Linus Pauling Therapy to reduce Lp(a)

December 8, 2018

Linus Pauling wrote that taking 6,000 mg of Vitamin C and Lysine daily along with 2,000 mg of Proline will reduce Lp (a) to safe levels. What are your thoughts and would you ever consider getting a colleague to run such a study?

How will drops in the insulin to glucagon ratio affect autophagy?

December 8, 2018

The insulin to glucagon ratio is affected very much by the macronutrient ratios and metabolic conditions of the individual. For instance, Ben Bikman has referenced that: – While Fasting you have lower insulin and more glucagon: ~0.8 – While eating the Western Diet with higher carbs there’s more insulin: ~4.0 – On a Low Carb…

Blood Pressure. How do you get the most accurate result?

December 8, 2018

Sit quietly before for 5 min? 10? Average of three readings? One minute in between? Two? Take three times a day for a week? Month? When should a continuous blood pressure monitor enter the picture? Basically, give me all you got on getting the most accurate and reliable measurement of blood pressure over a given…

What is the best way to track progression/regression of CVD? Both you and Dayspring discounted CAC and CIMT if on drugs. What’s left?

December 8, 2018

Peter I have not heard you discuss blood pressure medication. Are they safe? Are there concerns with long time use? Also what are your thought regarding the new guidelines?

December 8, 2018

My wife and I would like to know if you are taking on new patients

December 8, 2018

How does letrozole help treat endometriosis?

December 8, 2018

My girlfriend has endometriosis, in the past year I’ve gotten her to go from eating fries to eating healthier, and now we’ve been on keto for around 2-3 months. She seems to be getting better. She reduced the dose of her letrozole from 2.5 everyday with progesterone, to a 1/4 every other day then every…

Would a relatively healthy individual benefit from taking probiotic supplements? Is it better to obtain probiotics from diet or supplements? Must they be taken everyday?

December 8, 2018

Hi Peter, I watched a podcast you spoke on during the Joe Rogan show. I am a type 1 diabetic and I’ve been told that because I’m taking insulin, my progress in the gym is basically due to steroids. my question for you is, does taking insulin as a diabetic change or increase my muscle building abilities? thanks

December 8, 2018

If I responded badly to keto, and improved when switching to mufas. And I carry apoe4 (hetero), and some FUT genes. Should I be eating seafood? Or eggs? I.e., should I worry about cholesterol absorption? Should I check phytosterols to eliminate this option? Furthermore, should I be careful not to take grape seed extract or somehow reduce phytosterols frim my diet?

December 8, 2018

Thanks!

Why would someone want to use a CGM to dose insulin if they don’t have diabetes?

December 8, 2018

You mentioned the reason the FDA is unlikely to allow CGM’s into the public market is due to the fact that some non diabetics would use it to dose insulin. Who would do that and why?

what you think and/or know about Trans-D developed by Dr. Buttar? and all related products sold and endorsed by Dr. Buttar on www.InfoOnAging.com; also how about bioidentical hormones pros and cons

December 8, 2018

I have been trying to understand the risks of bioidentical hormones and reading Dr. Buttar’s book, ” the 9 steps to keep the doctor away” I learned about his Trans-d formula and the risks on taking bioidentical hormones. Thank you for all wonderful endeavors and reaching out to so many people with excellent information.

Hello Peter, thanks for the great job you are doing with the podcast. I am really struggling with one fundamental thing. We all know how exercise is good, especially because (as you mention many times) it makes you more insulin sensitive. When I do fasted exercise (usually HIIT or strength), however, I noticed that by BG usually increases significantly, and I assume insulin will bring it down again to normal levels after exercise. I do both IF and Keto to avoid insulin spikes, but then HIIT lilkely spikes my insulin? can you elaborate on that? Thankss form Italy

December 8, 2018

Referrals to Specialists – Convincing Your GP

December 8, 2018

Hey Peter – I’m listening to your podcasts and taking a deeper dive into test results and the feedback I have been getting from my GP. After your in-depth discussions on cholesterol and my annual blood test showing “high” LDL, my GP’s advice of changing diet and a blood test again in three months seemed…

What is the optimal frequency of intimate sexual contact, and is there sexual dimorphism or interaction with patterns of hormonal fluctuation?

December 8, 2018

Can you explain nutritional/exercise do’s and don’t’s for someone just getting started?

December 8, 2018

The podcast and all of the info you put out is great, but I find myself (with very limited knowledge related to the medical field/science) lost a lot. You have a wealth of advanced info, but how does someone start? Ketosis, intermittent fasting, exercise routines/motivation, etc. Any entry-level advice or resources? Thanks!

I’m very interested in the use of sauna’s for longevity and curious as to Peter’s opinion on the near- and far- infrared saunas in comparison to very hot dry, finnish saunas from a longevity standpoint. I’m concerned that many are touting that long-term data on dry saunas applies to infrared, and that this may be premature. However, I use a near infrared sauna and find that I sweat nearly as much, but miss out on the endorphin rush post-dry sauna. Thanks!

December 8, 2018

Lightning round: can you name 5 watch brands that are overrated/underrated?

December 8, 2018

still waiting for the full episode devoted to wrist watches…

What are Aspartame effects on health?

December 8, 2018

Can’t seem to find anything bad about this, but curious how detrimental my Diet Coke addiction might be. Seeing some science to backup it sucks would kick me into gear to ditch it!

Top 5 things parents can do to optimize their children’s health?

December 8, 2018

What do you think about CBD for health? Risks/benefits?

December 8, 2018

Also just MJ in general

What is the next best thing after Dexcon G6 for an ordinary consumer?

December 8, 2018

Do you have any tips / to-dos for people who are underweight but seemingly healthy?

December 8, 2018

Sauna benefits–What kind of sauna should I buy, steam, near of far infared, wet or dry?

December 8, 2018

I have heard Dr. Rhonda Patrick and you talk about how great saunas are and how they can lower all cause mortality and improve muscle building and increase cardiovascular health. But when I look to buy one, I am confused as hell as to which kind I should get and there seems now to be…

Diagnosing food intolerances and allergies

December 8, 2018

I had a blood test probably over ten years ago and a skin prick test. I am thinking that I should have another test done, but I am wondering how much has advanced since then. Can you give some guidance on how to go about diagnosing food allergies and intolerances and how to go about…

Please: A rant about a fonts. How to choose beautiful font couplings, what makes a bad font, how you developed a passion for them and became an astute user of fonts.

December 8, 2018

Only after hearing you criticise fonts did I notice the prolific use of fonts in your site, and how they all compliment each other. This made me super conscious of how I use them in my site so would love to hear a Font 101 from the Attia himself.

During the last AMA (on video) you teased the possibility of doing a few whiteboard discussions for more depth. I would love to see such an episode (or episodes) on endocrine issues, specifically on common modern treatments fall short, eg. hypothyroidism.

December 8, 2018

Water fasting

December 6, 2018

Hi, I’m 61 yrs. I did a 5 day water fasting for the first time. I noticed my BP went up from 110/70 to 180/70 is that normal? Regards, Ana

I’m in my 30’s and am looking to make sure I don’t pass away from a heart attack like my father and grandfather did at around 60. What steps can I take to prolong the onset of Heart Disease.

December 6, 2018

I do a basic lipid panel (for free because I’m in Canada) every year to have a baseline but I feel as though I should get more. I tried to listen to the Dayspring Podcast but couldn’t follow along well enough. Should I get a full wellness FX heart panel at my age?

Hi Peter. I have a question about diabetes. I have never been diagnosed with it, nor have I ever needed to take insulin. However, I do have to eat carbs every 4-5 hours maximum, or else I get very sick. Recently, a doctor I went to asked for me to get my C-peptide checked out, and it came out low (0.82 ng/ml; the normal range being 1.10 to 4.40). With that result, my doctor said there wasn’t a solution for it. I would like to try intermittent fasting and/or a ketogenic diet, but it is impossible for me for this reason. Is there anything I could do? Thank you very much. Greetings from Seville, Spain

December 6, 2018

Winner of the Nobel for describing the regulation of cholesterol metabolism, Michael S. Brown teaches that the primary source of a cell’s cholestetol is delivery by LDL. Tom Dayspring teaches the primary source of a cell’s cholestetol is intracellular synthesis. Furthermore, Brown said that habitually high dietary cholesterol will be shuttled by chylomicrons to the liver, over time causing liver cells to fill up with cholesterol, and the cell’s feedback response is to down regulate LDL receptors raising LDL-P. Love to hear your thoughts

December 6, 2018

Women’s health resource, HRT, etc. ANYONE out there in podcastland you would recommend?

December 6, 2018

The dearth of MD’s that give a shit about continuous learning is astounding.

Does Oral supplementation of Lysine or Proline decrease Lp(a) binding to the arterial wall?

December 6, 2018

As a heart attack survivor, and triple bypass patient, I’ve subsequently read “consumer-level” information on the subject of preventing and possibly reversing heart attacks, with the hopes of optimising my (remaining) future health. Maybe too late, or maybe “better late than never”? Because I do not have access to the top medical research sites/reports, I…

Who is an expert in Chronopharmacology ?

December 6, 2018

When . . . we take meds or supplements can affect efficacy . . . Chronopharmacology: New Insights and Therapeutic Implications https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885389/ https://www.researchgate.net/publication/292990133_Chronobiology_and_Chronopharmacology

An idea for monetizing your podcast?

December 6, 2018

Figure a way to get approval for CMEs in some of these deep dives. As a licensed provider I am willing to pay for that. The lipid series could have been made into credited hours for DCs NDs RNs MDs and so on . Sorry didn’t know where to go on the site to make…

Treatment for Hyperthyroidism or Grave’s Disease

December 6, 2018

What podcasts do you listen to?

December 6, 2018

Alternatively what podcasts would you recommend people avoid? Not so much from a this person is horrible perspective but with someone like Ben Greenfield for instance who produces a lot of content – how do you reduce the noise compared to the content. Your work is incredibly thoughtful and involves a lot of deep thinking…

I have been told Ketone (BHB) blood levels do not necessarily describe ketone metabolism. Is there a way to measure Ketone utilization outside of merely Ketone Blood levels?

December 6, 2018

What qualifications do you require of your research analysts?

December 6, 2018

I would like to apply for a position at some point in the future. I’m pursuing a computer science degree and would like to find an organization to work with where I can combine my morbid curiosity to disprove conventional beliefs about nutrition and general health using existing data. My entire purpose for pursing computer…

I’ve been reading more literature on the seeming myriad health benefits of fasting and time restricted eating. One question I have is on the legitimacy of minimal metabolic adaptation via fasting as a vehicle for fat loss.

December 6, 2018

About 4 years ago I lost about 50lbs on the Slow Carb Diet but then plateaued hard, fell off the wagon due to a handful of life circumstances, and over the next 4 years I gained most of it all back. A few months ago I re-dedicated myself, but this time I was armed with…

Hi Peter, I saw that on Dr. Rhonda Patrick’s podcast in 2016 you stated that you were a sceptic waiting to be convinced in regards to the Microbiome and its effect on the body and how one can treat it. I was wondering if the science over the past few years had convinced you and what your thoughts are now? Thank you

December 6, 2018

What do you think of the paleo-ketogenic diet? Or carnivory? Particularly for reversing autoimmune disease.

December 6, 2018

Would you consider moderating a conversation between Dr Shawn Baker (carnivore diet) , Zsofia Clemens (PKD Clinic in Hungary) and say someone like Rhonda @foundmyfitness? I’d be interested to see if there could be some agreement, if people are open to looking at the science. Everyone seems to make a good case, but they say…

Possible downside to HUMANS of this NEW THERAPY that causes 1/3 FAT LOSS in only 18 days…in mice?

December 6, 2018

I understand this research is in its early stages. Please comment on the POSSIBLE harm to humans by accelerating fat loss in this manner? I am curious about the long-term POSSIBLE downsides to this therapy. Georgetown University-led study found that forced expression of protein FGFBP3 (BP3 for short) might reverse disorders associated with metabolic syndrome,…

Blood glucose and sex? Do you expect sex to raise or lower blood sugar and why?

December 6, 2018

I’ve read sex is comparable with exercise and will bring blood glucose down. However, me and my partner are both in nutritional ketosis and we usually see a non negligible spike in glucose. One example, I was 81mg/ml and 2.7mmol/l at 8pm, and 100mg/ml and 1.2mmol/l at 1.30am, after sex, and with no food intake…

You are taking measures to reduce cardiac factors on yourself. What would you do if you had cancer risk?

December 6, 2018

Hi! As an engineering student with a great internet in medicine and longevity, I would love to hear you riff around the following: If you were not an ME bit still had an engineering background and you wanted to do something that could potentially move the needle, where would you start looking? What are the obvious problems that could be solved by engineering rather than biochemistry?

December 6, 2018

When you appeared on Jocko Podcast, you mentioned that you taught calculus over the years. What are some principles and concepts that you tried to emphasize more that you feel is missed by other teachers? Do you have any general thoughts on the optimal process for complex areas like advanced linear algebra, multi variable calculus and stochastic calculus?

December 6, 2018

Do you have any thoughts regarding ME/CFS? I am not afflicted by this condition myself, but I think it is a very fascinating (and awful) syndrome, which is mostly treated with lifestyle interventions. There seems to be a clinic that treats these patients with Rapamycin in Texas.

December 6, 2018

You talk a lot about sleep on the podcast, and it seems especially important for ApoE-4 positive individuals. I am a quite hardcore engineering student and I try to optimize my sleep by using melatonin to make sure I fall asleep at the exact time everyday. Could you share your thoughts about melatonin and the tradeoff between consistent sleep with melatonin vs less consistent sleep without it

December 6, 2018

Hi Dr. Attia, Can you please describe on your thoughts on supplements for longevity and anti-inflammation like wheat germ (spermidine), astaxanthin, spirulina, cacao, inulin, flax/chia seeds, turmeric, cinnamon etc. Thanks!

December 6, 2018

What are some best practices (and pitfalls) for testing the efficacy of a particular intervention?

December 6, 2018

You’ve mentioned the utility of trying individual interventions and seeing what works for a particular patient, rather than just relying on generalities and averages. And we now have access to a lot of biometric data gathering devices and individual lab results to help with that. But I think many providers and patients suck at using…

Post-Workout Carbs

December 6, 2018

Does consuming simple carbs after either a HIIT cardio workout or resistance workout replenish muscle glycogen or does it replenish just liver glycogen? What do you think of 1% fat, chocolate milk as a post-recovery drink if it contains 28 grams of sugar? (yes, this is a Canadian asking)

Oura accuracy

December 6, 2018

Hi Peter, Have you compared the Oura 1st gen vs 2nd gen? I’ve compared and there is a huge deviation in all the sleep metrics. Deep sleep can be 2 hours off each night as well as REM sleep. The data almost never matches. I’ve contacted Oura and they even replaced my ring as the…

If my gradparents had a few sorts of cancers (colon, bladder), and I am serious about life style changes, what’s the best way to reduce my risk?

December 6, 2018

Thanks

Bad response to keto- does it include hyper absorption of dietary cholesterol?

December 6, 2018

I had a bad response to keto, ldlc dropped back down when I switched to MUFAs. I am wondering about eggs and seafood as protein sources but I am afraid I might be absorbing dietary cholesterol. I also carry one apoe4 gene, and FUT genes. Thanks.

What are the most common misconceptions about health? Especially ones with greater impact or severity.

December 6, 2018

What is in your fridge and pantry at this moment?

December 6, 2018

Do you workup patients for Patent Foramen Ovale?

December 6, 2018

EPA/DHA intake considerations: dosage and form

December 6, 2018

You touched on the question of EPA/DHA in some of the podcasts, could you expand on this topic? What are your thoughts on supplemental omega-3 FA intake for the prevention of CV and neurodegenerative disease? Daily dose, source, form (e.g. triglyceride vs. phospholipid)? Would different strategies apply for different priorities?

Peter, I am a practicing Physical Therapist and after listening to your podcast, I have the urge to do more for my patients/future patients. Most patients have a plethora of issues beyond the scope of a PT (uncontrolled diabtetes, high BP, opioid addiction, etc) and though as I PT I can provide education to why it’s in the patient’s best interest to take control of these issues, I really am limited to either giving them their referring physician a call/requesting the patient follows up with their physician. Truthfully, a return to med school would be out of the question for me, but I was curious on your thoughts on going back to school to be a PA along with being a PT. In your eyes, would returning to school to become a PA be a worthwhile endeavor in an attempt to bring a more multi-disciplinary approach to my patients? In your experience, can PA’s provide comparable care to a patient as a PCP? Thanks for the insights.

December 6, 2018

How do you record, organize, and track all of the data you measure (blood glucose, cholesterol levels, sleep, diet, etc.)? Do you have all the data in a single place or in separate places (such as various apps)?

December 6, 2018

I’m trying to figure out the best way to track my health data to see trends over time.

Can you give a breakdown of how you spend your time in a typical week? How do you balance your pursuit of work and other personal interests (e.g. exercising, driving, archery, etc.) with your family commitments?

December 6, 2018

Atherosclerosis: what techniques can be used to halt, and reverse build up of plaque, and/ or calcification withi arteries?

December 6, 2018

What baseline and followup tests have you done for heart disease and why? eg coronary calcium scan, angiogram, other etc.(You said you were worried about a family history of heart disease). And what were your results, and what are your actions to mediate the risks?

December 6, 2018

Do the benefits of fasting trump the loss in lean body mass in women over 60?

December 6, 2018

Thank you for including a section on females in AMA#3. I wish there were more information on older age groups. I am over 60 and spend a lot of time and money on nutrition and exercise to maintain fitness and mental clarity. My understanding is that losing lean body mass is not a good thing…

What is the most actionable, consumer-available, wearable device to improve overall health? And can you give examples of how this product has enabled you to improve your health?

December 6, 2018

G’day Peter, would love to hear your thoughts on Bruce Ames’ nutrient triage theory. Do you think subclinical and obscured quasi-deficiencies in particular essential nutrients may lead to poorer health outcome and a potentially earlier death?

December 6, 2018

I do TRF and often eat one meal per day which leads to less overall food intake and decreased nutrient diversity and this is forever quietly playing on my mind. Cheers

How can women increase bone density after menopause.

December 6, 2018

Should patients over 60 years old or anyone actually take amino acids to increase muscle mass?

December 6, 2018

I have Met Syndrome w mod-severe small fiber sensory neuropathy. Pain managed on tramadol. I have done low carb w hopes of getting into nutritional ketosis. Problem is that as soon as my BS appropriately begins to fall and I begin making ketones, my neuropathy pain flares totally out of control and I’m forced to stop. When my neurologist heard that, he was very upset, not about what I was attempting, but the fact that such an exacerbation of pain could cause additional widespread nerve damage!!

December 6, 2018

Wasn’t finished w my question re: exacerbation of neuropathy pain on low carb w intermittent fasting.

December 6, 2018

If applicable, what is your take on the book “Perfect Health Diet” and/or the work of Paul Jaminet?

December 6, 2018

Assuming health technology will continue to advance, at what point/year do you think customized nutrition/exercise programs can be developed per each individual? Something like 23andMe for health/nutrition. Take a test at the doctor and they provide you a customized path for optimal longevity (based on current research)

December 6, 2018

I guess one of the hardest parts to consider is the general consensus of what is considered healthy. Eat this not that. Work out this not that.

2 months in: Low/no morning fasted ketone blood/100+ glucose

December 6, 2018

My wife and I are 2 months in on keto. Watching macros closely with MFP. Testing with Precision Xtra (Glucose/Ketones) most mornings. I have yet to reach more than .4 mmol on any given morning. My glucose varies between 97-122 with the rare samples being under 100. My normal mostly plant-based diet glucose was in…

Can you speak to the clinical utility of the endoPAT test for endothelial dysfunction? It’s purported to precede even coronary artery calcium scoring in predicting heart disease.

December 6, 2018

How does one go about procuring Topo Chico the most effective way possible?

December 6, 2018

In reference to monetizing the podcast, what do you think about listeners paying for the content that also incorporates their (our) biomarkers being included in the data sets for you to comment on collectively?

December 6, 2018

Healthy user bias acknowledged in this idea, people often get a kick out of A, being part of a tribe (cohort) and B, feeling they are paying for something that is inclusive of them. If your team put together a blank ‘spreadsheet’ of the biomarkers of your choosing to be filled in by paying listeners/participants,…

What is your opinion of quest bars? I know you have mentioned the rule of not having something if it comes in a packet but would like to know if quest bar would be an exception?

December 6, 2018

Have you tried Dr. Goodman’s Foundation Training?

December 6, 2018

I read Dr. Goodman’s books “True to Form” and “Foundation” and wondered what you think of his Foundation Training?

Great Interview with David Sinclair. Did David say he believe’s Tru/Niagen and Elysium/Basis can increase NAD in the cell? I believe you indicated that Josh Rabinowitz findings say no, only Intravenous, confusing?

December 6, 2018

Hi Peter, hope all is good, just did a lab test afer a fasted workout and sugar and lipids are higher then ussual, first time doing BW after fasted workout, is it possible that the Fasted Workout raises Sugar and Lipids count? momentarily?

December 6, 2018

If the components of cholesterol (particle, Lp(a), etc) are known to lead to cardiovascular disease and these components increase with consumption of a high saturated fat diet (eg Keto), could one take a prophylactic statin for cardioprotection during such diet to mitigate the potential harmful effects of the cholesterol?

December 6, 2018

What is your opinion on Halo? Is this legit?

December 6, 2018

Hi Dr. Attia. Thank you for all that you share via the podcast and website! As a first year family medicine resident very much interested in preventative medicine, I am keen to learn more about the non-conventional topics that you talk about that we are not traditionally taught about in residency/medical school (i.e. LDL particle size, APOE, etc.). However, when researching where to look for extra training on these topics, the specialty of “functional medicine” keeps reappearing in my search. Is this something you ascribe to? What is your thoughts on this field? Would you have any other education recommendations for me in order to become more literate on these topics?

December 6, 2018

Does the Rabinowitz paper entitled “Quantitative Analysis of NAD Synthesis-Breakdown Fluxes” argue convincingly against taking oral NR or NMN as a means to increase NAD?

December 6, 2018

Then are Basis & Chromadex a waste of money? Does the paper conflict with other findings?

What do you think about elevated TMAO levels potentially increasing CVEs?

December 6, 2018

Circulating trimethylamine N‐oxide and the risk of cardiovascular diseases: a systematic review and meta‐analysis of 11 prospective cohort studies Jiaqian Qi 07 Aug 2017

What is the best way to use BCAAs?

December 6, 2018

Any information related to BCAAs would be appreciated. I am an athlete and work out six to seven days a week, but have never used BCAAs. I am interested in gaining muscle and speeding up recovery.

Please deep dive on women’s health. Hormone replacement therapy – safety, efficacy, best practices? In what ways, if any, should our approach to longevity and health span differ from that of men and/or current standard of care.

December 6, 2018

I am so very grateful for the work you do! Thank you for sharing your brain with the rest of us! Keep it coming!

Do you have any experience with nerve tingling or numbness while keto? What can be done about this? Sometimes it wakes me up in the middle of the night.

December 6, 2018

I’m also wondering if muscle spasms are related to this.

Regarding Cortisol reduction, what are the best ways to test cortisol levels and the best way to reduce high cortisol?

December 6, 2018

We hear a lot about anxious people having higher levels of cortisol and how high cortisol affects sleep, weight loss, memory, etc? Besides the various blogs saying stress reduction is the main tool to reduce cortisol, are there any other effective methods? Thanks in advance

If one’s goal is weight loss and body fat reduction, do you recommend using exogenous ketone supplements? I have heard from a few folks such as Dr. Berg and Mark Sisson suggest that exogenous ketone supplementation can shut down lipolysis since the body stops producing its own endogenous ketones.

December 6, 2018

Where is a good place to start to researching the benefits of lifting weights and muscle mass?

December 6, 2018

I work with several young student-athletes a part of a sports team that have a resistance to lifting weights. Personally, I have found a myriad of benefits of lifting weights physically and mentally after listening to several people’s ideas, including your own. I can tell people to lift weights but I have inclinations that this…

Does the Rabinowitz paper entitled “Quantitative Analysis of NAD Synthesis-Breakdown Fluxes” argue convincingly against taking oral NR or NMN as a means to increase NAD? I heard in the Peter Atia podcast that you do take NMN? Love your work, and can’t wait to read your book! David A. Sinclair Ph.D., A.O. is now a connection David A. Sinclair Ph.D., A.O. David A., thanks for connecting! Hope you’re doing well. In that podcast with Ssinclair regard Sirtuins, I believe he said that NMN and NR oral intake did increase cellular levels of NAD. yet the Rabinowitz paper suggests that these entities are converted to nicotinamide in the liver. If that were true, how then would NAD increase, unless it was converted from nicotinamide? Is that possible? Would love you to explain all this!

December 6, 2018

What would Peter do / test for / try if he developed Tinnitus?

December 6, 2018

Assuming that the “basic” things have been checked by an ENT and no obvious root cause could be found. Also: assuming the Tinnitus is not induced by extreme noise and there is no hearing loss. Thanks.

What are your thoughts on fasting for people who have a hard time putting on weight and/or who don’t seem to do well/crash and burn on low carb diets? How about for people who are already stressed and exhausted, ie young parents etc.

December 6, 2018

Resveratrol Supplementing dosage, brand recommendation?

December 6, 2018

In your podcast with David Sinclair you mentioned that several or most of your patients take the Elysian supplement but you didn’t endorse or sign off on the supplement. Are there other providers you would recommend? Is David’s dosing of up to a gram reasonable?

What are the 8 Components of longevity and healthspan?

December 6, 2018

In a 2016 update, you mentioned nutrition as one of 8 components of longevity and healthspan. What are the other 7 components? Thanks, I absolutely love the podcast and show notes.

Wonder about your thoughts on some papers showing that AMPK activation may provide a survival advantage to some kinds of cancer cells, and therefore whether metformin would be beneficial for anticancer properties

December 6, 2018

https://doi.org/10.1038%2Fs41556-018-0126-z

What relationship (if any) are there to the Ketogenic diet and increased uric acid levels?

December 6, 2018

Or more generally, is there a framework on how one should think about uric acid levels in the context of DR and CR?

Will you please reveal your curry recipe?

December 6, 2018

Why do so few centenarians die from cancer, 4%, what the hell? Could it be the the non-trivial % of codes that are reported as death by “old age”(which is ridiculous btw) are missing cancers that are largely asymptomatic but with no autopsy we didn’t know?(I have no clue just speculating)

December 6, 2018

What are your current thought on TACT trial results and Chelation

December 6, 2018

I always appreciate your statistical insights and teachings on these topics

Do you think the human appetite can be biased towards a certain macro eg. Carbs, protein, fat

December 6, 2018

Peter can you comment on Eran Segal and his team’s work around the”Best diet for ME” (different macro-nutrient compositions evoking different glucose/insulin responses)?

December 6, 2018

In the Dr. Dayspring Part IV podcast, you discuss that zetia mono-therapy might work if you picked the right person. Could you elaborate a little on an ideal candidate? Maybe someone with close to normal desmosterol numbers and very high cholesterol absorption numbers?

December 6, 2018

Hi Peter, you said you gave several lectures on lower back health after your injury. Could you please give us a summary? Thank you.

December 6, 2018

What are your recommendations for best medical journals and other research/ news sources for people (non physicians and physicians) that want to learn more and stay up to date with best practices for diabetes, neuro degenerative disease, cancer, etc.?

December 6, 2018

Peter-Taking into account the risks of deadlift/squat, what alternative exercises do you do? yOUR EXERCISE ROUTINE?

December 6, 2018

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