Reducing heavy alcohol intake: a lifeline for cardiovascular health
Can reducing heavy alcohol intake significantly lower cardiovascular risk, or is the damage already done?
#304 – NEW: Introducing quarterly podcast summaries – Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more
“Getting a high VO2 max and being very strong are very hard to do. They take a long time. Everybody can do them, but they can’t be done quickly and easily, so therefore, they are the tip of the spear.” —Peter Attia
High Lp(a) warrants intervention, even without other cardiovascular risk factors
A new study shows that the oft-ignored metric is strongly associated with heart attacks, regardless of the presence or absence of standard modifiable risk factors for cardiovascular disease
#303 – A breakthrough in Alzheimer’s disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer’s disease | Dena Dubal, M.D., Ph.D.
“I have this dream that people might be able someday to benefit from klotho, this factor that naturally circulates in our body, that helps with longevity, that helps with other organ systems and enhances the brain.” —Dena Dubal
#302 – Confronting a metabolic epidemic: understanding liver health and how to prevent, diagnose, and manage MAFLD and liver disease | Julia Wattacheril, M.D., M.P.H.
“The average person you’re seeing with MASLD is much more at risk for cardiovascular-related outcomes and malignancy-related outcomes from their metabolic health than they are for liver-related risks.” —Julia Wattacheril
#301 – AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it
“Inflammation really becomes chronic once it’s persisted for several months, but it can persist for much longer than that.” —Peter Attia
Can ovarian cancer be detected by genetic analysis of cervical cancer screening samples?
A proof-of-concept method for adding ovarian cancer screening to existing protocols
Body composition: impact on disease risk and how to assess and improve it
A refresher on why you should care about body composition and a practical guide to determining and interpreting your measurements
#300 – Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise?
“The probability that having a high VO2 max, high muscle mass, and high muscle strength are going to increase the length of your life and improve the quality of your life. . .is so high that to act in disregard of that is irresponsible.” —Peter Attia
Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna’s death
“Senna lived 10 lives in his 34 years. And not only that, he’s one of the few people who still matters in his death.” —Peter Attia