“The single greatest risk to my longevity is my lower back.” —Peter Attia

“We can’t keep hitting the same pillar and expect that we’re going to cure cancer. . .we need the activators of the immune system, we need the inhibitors of the activated oncogenes, we need the drugs that target epigenetic regulators, and we need the metabolic switch regulators.” — Keith Flaherty

“This is where an MRI becomes a beautiful machine in the fact that it actually allows you to take the ‘yes or no’ binary answer of functional nuclear medicine and combine it with the anatomic localization and understanding of tissue types of radiology. . .I merged those two together on the one machine.” — Raj Attariwala

“I was surprised by how much fun I had doing this, I was surprised by the feedback we got from folks that kind of dug it, and so even if the world doesn’t need another podcast, we’re just gonna keep doing this.” — Peter Attia, reflecting on the first year of doing the podcast

“We don’t want [people] to be afraid of the bad outcomes. . .because we would like people to be innovative and push against the status quo because that’s how we move forward as a society, as a business, as an individual.” — Annie Duke

“We think of all these responses, obesity, insulin resistance, and the beta cell failure, as pathologic. They’re actually protective.  . .Your body is actually trying to protect itself against the root cause of the problem which is too much insulin, too much glucose.” — Jason Fung

“[Sleep] is like that master volume button on a mixing deck that you see in the studio. You can manipulate each one of those dials, or you can go to the far left and just move that one dial…and all of the other levers seem to move with it.” — Matthew Walker

“I came alive through that process. . .I was already alive in the studio, but maybe that was the only place I was alive before. But through exercise, I became alive more in life.” — Rick Rubin on how exercise changed his life

“Leading a family is the same way you lead an organization or lead a team. If you bark orders at your team, your team won’t like you, they won’t respect you, and they’re not going to carry out those orders with any sort of commitment.” — Jocko Willink

“Humility is the most important attribute or characteristic for a leader to have.” — Jocko Willink