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Recent Podcasts

Diseases

#52 – Ethan Weiss, M.D.: A masterclass in cardiovascular disease and growth hormone – two topics that are surprising interrelated

“Primary prevention is still very much art and not science and probably will be for our lifetime so we’ll have to get used to that.” —Ethan Weiss

Podcast

The Ayrton Senna Episode (re-release): Celebrating the greatest driver in Formula 1 history and the cautionary tales of driven individuals

To celebrate the life of the legendary Formula 1 driver Ayrton Senna, 25 years to the day of his tragic death, we are re-releasing this bonus episode. In this episode, Peter and med school colleague (and brilliant psychiatrist) Paul Conti reminisce on their favorite moments in Formula 1 history, their deep admiration for the late…

Mental health

#51 – Robert Sapolsky, Ph.D.: The pervasive effect of stress – is it killing you?

“The [stress response] system has been serving vertebrates, doing a lot of help for them for an awful long time, and it’s only been a very recent modification to instead secrete [cortisol] in response to thinking about taxes.” —Robert Sapolsky

Aging

#50 – AMA #5: calcium scores, centenarian olympics, exercise, muscle glycogen, keto, and more

“We’re really talking a completely new model, which is actually forcing your way to become a centenarian rather than just sort of gliding your way into it and therefore, I think it’s going to require much more deliberate attention around what your mind and body are doing at that point and time.” — Peter Attia

Sleep

#49 – Matthew Walker, Ph.D., on sleep – Part III of III: The penetrating effects of poor sleep from metabolism to performance to genetics, and the impact of caffeine, alcohol, THC, and CBD on sleep

“Lack of sleep is like a broken water pipe in your home. It will leak down into every nook and cranny of your physiology.” —Matthew Walker

Sleep

#48 – Matthew Walker, Ph.D., on sleep – Part II of III: Heart disease, cancer, sexual function, and the causes of sleep disruption (and tips to correct it)

“If there is one central, common pathway through which we can understand almost all aspects of the deleterious impact of insufficient sleep, it is…an excessive leaning on the fight or flight branch of the nervous system.” — Matthew Walker

Sleep

#47 – Matthew Walker, Ph.D., on sleep – Part I of III: Dangers of poor sleep, Alzheimer’s risk, mental health, memory consolidation, and more

“I think that sleep may be one of the most significant lifestyle factors that determines your risk ratio for Alzheimer’s disease.” — Matthew Walker

Nutritional biochemistry

#46 – Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease – NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine and more

“People are gonna make a decision to. . . either wait 10 or 20 years until we know something better, or you take the position that you’re going to tinker. And if you’re going to tinker, you’re a lot more successful if you have a working model of what’s going on than if you don’t.” —Chris Masterjohn

Sleep

#45 – AMA #4: sleep, jet lag protocol, autophagy, metformin, and more

“Every day in the human body, some 10 billion cells die and are replaced by new cells.” —Nick Lane

Podcast

#44 – Jeremy Schaap, ESPN journalist: upsets, doping, triumphs, and the importance of sports

“Fairness is the underpinning of everything. It’s not just about being fair to the subject. It’s about being fair to the audience. It’s about being fair to the story, and fair to the truth.” —Jeremy Schaap

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