#66 – Vamsi Mootha, M.D.: Aging, type 2 diabetes, cancer, Alzheimer’s disease, and Parkinson’s disease – do all roads lead to mitochondria?
“We have 300 different forms of monogenic mitochondrial diseases. . .and these are terrible diseases and we need therapies for them. . .but it’s also our hope that studying some of them will provide insights into the common form of aging as well.” —Vamsi Mootha
#45 – AMA #4: sleep, jet lag protocol, autophagy, metformin, and more
“Every day in the human body, some 10 billion cells die and are replaced by new cells.” —Nick Lane
The mouse trap: lost in translation?
“The great majority of how we understand disease, and attempt to cure it,” writes Engber, “derives from a couple of rodents.” About 4/5ths of all animal studies reported in biomedical research papers from 1950-2010 were done in rodents (59% in mice, 18% in rats).
#37 – Zubin Damania, M.D.: Revolutionizing healthcare one hilariously inspiring video at a time
“The idea that you can optimize a particular regiment to the goals of that unique patient is the foundation of what we call Health 3.0.” —Zubin Damania