Category

COVID-19

Aging

#123 – Joan Mannick, M.D. & Nir Barzilai, M.D.: Rapamycin and metformin—longevity, immune enhancement, and COVID-19

“I think what the mTOR inhibitors are doing is not stopping people from getting infected [with a virus], but if you get infected, there’s a better immune response and your symptoms will be milder.” — Joan Mannick

COVID-19

#117 – Stanley Perlman, M.D., Ph.D.: Insights from a coronavirus expert on COVID-19

“There’s really no evidence so far that says this virus has changed in a way that makes it unlikely a vaccine will work, unlikely that a previous infection will protect you from a second infection–there may be reasons why it won’t, but it won’t be because the virus is changing.” — Stanley Perlman

COVID-19

COVID framework: How does this thing end?

I tried to explain to my 5-year-old son where we currently stand in this pandemic. His questions are the ones that truly matter right now.

COVID-19

#115 – David Watkins, Ph.D.: A masterclass in immunology, monoclonal antibodies, and vaccine strategies for COVID-19

“As we stand here with the coronavirus epidemic three months old, I think we should have faith that science will find a solution to this.” — David Watkins

COVID-19

SARS-CoV-2 and the host response: psychological stress

I’ve been thinking a lot about the role of psychological stress and how it relates to our response to SARS-CoV-2, the virus that causes COVID-19.

COVID-19

COVID-19: What’s wrong with the models?

Originally written as an internal memo on April 15, 2020; updated and shared publicly on April 20

COVID-19

#107 – John Barry: 1918 Spanish flu pandemic—historical account, parallels to today, and lessons

“Society is based on trust. When trust evaporates, society begins to fray.” — John Barry

COVID-19

How to interpret screening tests: video, spreadsheet, and primer

An overview of how to interpret screening tests for COVID-19 (and diagnostic testing & screening in general).

COVID-19

#106 – Amesh Adalja, M.D.: Comparing COVID-19 to past pandemics, preparing for the future, and reasons for optimism

“All of that makes me very optimistic that we will be able to meet the challenge of this virus without putting any of our hospitals into crisis, that this is going to be a severe challenge for this country, but it’s not something that that is going to break the country.” — Dr. Amesh Adalja, referring to some lesser discussed positive trends

COVID-19

#105 – Paul Conti, M.D.: The psychological toll of a pandemic, and the societal problems it has highlighted

“The virus isn’t plotting against us. It doesn’t have intelligence. It’s invisible. In order to unite, we have to recognize our shared humanity.” — Paul Conti

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