Exercise

Guest Episode

Translating the science of endurance and extreme human performance

Ep. #151 with Alex Hutchinson, Ph.D
Medications & supplements

Guest Episode

A modern Renaissance man's journey through science, politics, and business

Ep. #150 with Bill Frist, M.D.
Nutrition

AMA

Simplifying the complexities of insulin resistance: how it's measured and what we can do about it

Ep. #149 (AMA #20)
Longevity

Guest Episode

The gold standard for testing longevity drugs: the Interventions Testing Program

Ep. #148 with Richard Miller, M.D., Ph.D.
Cognitive Health & Neurodegenerative Disease

Guest Episode

Deep dive into the “Alzheimer’s gene” (APOE), brain health, and omega-3s

Ep. #147 with Hussein Yassine, M.D.
Mental & Emotional Health

Guest Episode

Emotional first aid and how to treat psychological injuries

Ep. #146 with Guy Winch, Ph.D.
Exercise

AMA

Zone 2 training, magnesium supplementation, and how to engage with your doctor

Ep. #145 (AMA #19)
Exercise

Guest Episode

Optimizing health and performance through maximal aerobic function

Ep. #144 with Phil Maffetone
Understanding science

Guest Episode

Why most biomedical research is flawed, and how to improve it

Ep. #143 with John Ioannidis, M.D., D.Sc.
Mental & Emotional Health

Guest Episode

The Bobby Knight story—a tale of unchecked anger, ego, and winning at all costs

Ep. #142 with Robert Abbott
Nutrition

AMA

Deep dive: sugar and sugar substitutes

Ep. #141 (AMA #18)
Risks

Guest Episode

A masterclass on insulin resistance—molecular mechanisms and clinical implications

Ep. #140 with Gerald Shulman M.D., Ph.D.
Mental & Emotional Health

Guest Episode

The Power of Self-Compassion

Ep. #139 with Kristin Neff, Ph.D.
Risks

Guest Episode

Alzheimer’s disease prevention—patient and doctor perspectives

Ep. #138 with Lauren Miller Rogen and Richard Isaacson, M.D.
Risks

Guest Episode

An expert perspective on COVID-19 vaccines

Ep. #137 with Paul Offit, M.D.
Nutrition

AMA

Body composition methods tour de force, insulin resistance, and Topo Chico

Ep. #136 (AMA #17)
Mental & Emotional Health

Guest Episode

How understanding death leads to a better life

Ep. #135 with BJ Miller, M.D.
Risks

Guest Episode

Preventing cardiovascular disease and the risk of too much exercise

Ep. #134 with James O'Keefe, M.D.
Risks

Guest Episode

Hallmarks of successful cancer policy

Ep. #133 with Vinay Prasad, M.D., M.P.H
Other tactics, tools, & treatments

AMA

Exploring hot and cold therapy

Ep. #132 (AMA #16)
Mental models

Guest Episode

Recognizing and overcoming cognitive dissonance

Ep. #130 with Carol Tavris, Ph.D. & Elliot Aronson, Ph.D
Risks

Guest Episode

The latest insights into cardiovascular disease and lipidology

Ep. #129 with Thomas Dayspring, M.D., FACP, FNLA
Exercise

Guest Episode

Evolution of the foot, running injuries, and minimalist shoes

Ep. #128 with Irene Davis, Ph.D.
Sleep

Guest Episode

Fasting, gut health, blue light, caffeine, REM sleep, and more

Ep. #127 with Matthew Walker, Ph.D.