November 18, 2019

Fasting

#80 – Celebrity AMA with Apolo Ohno and Sasha Cohen: Fasting, rapamycin, performance vs. longevity, and more

“I am obsessed with knowing stuff. There's just no denying it.” — Peter Attia

Read Time 15 minutes

In this special celebrity AMA episode, Peter answers questions from former Olympians and past guests, Apolo Ohno and Sasha Cohen, on a wide range of subjects including fasting, learning, training for performance versus longevity, and much more. If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed. If you are not a subscriber, you can learn more about the subscriber benefits here.

We discuss:

  • Apolo’s questions begin [1:45];
  • Why women may have a harder time fasting, and tips for those who are struggling [2:10];
  • Is there any place for fasting as part of a nutritional strategy in adolescents? [6:15];
  • Tips for learning and retaining large amounts of new information (and the best nutritional approach) [9:15];
  • Must read books of 2019 [14:45];
  • If you could only keep a few watches for the rest of your life which would they be? [16:45];
  • What workout would Peter do inside a hotel room? [22:15];
  • What is Peter’s ultimate gorge meal? [23:45];
  • How do you foresee fasting as a mechanism for performance in athletes? [25:30];
  • What is driving Peter to strive for excellence? [33:30];
  • Sasha’s questions begin [38:40];
  • What are you most excited about in the longevity space? [38:45];
  • At what point do you see enough data or proof that a new drug, or type of fasting is worth trying it out for yourself? [41:30];
  • Is it possible to obsess so much about your health that it becomes a negative stressor? [46:45];
  • Which tests are worth doing if you want to be proactive about your health? [48:15];
  • Are there any supplements Peter things are beneficial to be taking? [55:15];
  • How does Peter’s training differ when optimizing for performance versus longevity? [56:30];
  • How does taking testosterone and growth hormone affect performance versus longevity? [59:15]; and
  • More.

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Apolo questions begin [1:45]

Why women may have a harder time fasting, and tips for those who are struggling [2:10]

Apolo’s wife

  • Apolo and his wife practicing fasting
  • Apolo can go up to 7 days pretty easily
  • His wife really struggles after 72 hours
  • At that point she basically has no energy to even leave the house
  • She has no ability to do anything even remotely mentally strenuous

Peter’s thoughts:

  • Peter has noticed that his female patients have a tougher time with fasting (and even time restricted feeding)
  • He’s not sure why (maybe some evolutionary reasons)

–For people who struggle, Peter progress his patients as follows:

  • Once someone is able to consistently do 18 hr fasts with 6 hr eating window
  • He then moves them to 1 meal per day
  • Next will be a 36 hour fast

Fasting tips from Peter:

{end of show notes preview}

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  1. This post about longevity supplements is interesting. The human’s longevity depends not on what we eat as healthy food, but what we like to eat as a tasty natural food. Desirable food depends on our life style, and contribute a lot in our longevity that can be extended for very long time, almost indefinitely, as was discovered by Allen Omton and Serge Dobrow.
    John Logger

  2. Peter expressed interest in SGLT2 inhibitors, seeming to indicate he was at least considering using one himself. One key criteria he mentioned was animal lifespan data. the NIA’s ITP is now reporting that the SGLT2 inhibitor canagliflozin extended median survival of male mice by 14%, and maximum lifespan (tenth-decile survivorship) by 9%.
    https://doi.org/10.1101/2020.05.23.112763

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